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Suzuki-Miyaura cross-coupling of aryl and alkyl halides using palladium/imidazolium salt protocols

By Katherine Arentsen, Stephen Caddick, F Geoffrey N Cloke, Adam P Herring and Peter B Hitchcock

Abstract

A simple new protocol for the high yielding Suzuki-Miyaura cross-couplings of aryl chlorides with aryl boronic acids using a palladium/imidazolium salt catalytic system is presented. The first examples of a palladium/imidazolium salt protocol for sp3-sp3 Suzuki-Miyaura couplings of alkyl halides are also disclosed

Year: 2004
OAI identifier: oai:sro.sussex.ac.uk:15934
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