Evaluation of the Antitumor Activity by Ni Nanoparticles with Verbascoside

Mingyue Chen; Yaqin Zhang; Bin Huang; Xueming Yang; Yunong Wu; Bin Liu; Yi Yuan; Gen Zhang

oai:doaj.org/article:2dc0f4ed64024bb3b84099d545787012

Evaluation of the Antitumor Activity by Ni Nanoparticles with Verbascoside

Authors: Mingyue Chen
Yaqin Zhang
Bin Huang
Xueming Yang
Yunong Wu
Bin Liu
Yi Yuan
Gen Zhang
Publication date: 1 January 2013
Publisher: 'Hindawi Limited'
Doi

Abstract

Verbascoside (VB) has attracted a great deal of attention due to ITS pharmacological properties. In our study, we synthesized a multifunctional verbascoside coated Ni nanoparticles (VB-Ni). Transmission electron microscopy (TEM) and high performance liquid chromatography (HPLC) display the characteristics of VB-Ni nanoparticles. Compared with VB, VB-Ni has been proven to induce apoptosis and resist the growth of doxorubicin-resistant K562 cells in vitro and in vivo. Thus, VB-Ni nanoparticles can be thought of as an ideal mode of cancer treatment

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Last time updated on 18/12/2014

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