Article thumbnail

Hebbian Reverberations in Emotional Memory Micro Circuits

By Luke R Johnson, Joseph LeDoux and Valerie Doyere

Abstract

The study of memory in most behavioral paradigms, including emotional memory paradigms, has focused on the feed forward components that underlie Hebb’s first postulate, associative synaptic plasticity. Hebb’s second postulate argues that activated ensembles of neurons reverberate in order to provide temporal coordination of different neural signals, and thereby facilitate coincidence detection. Recent evidence from our groups has suggested that the lateral amygdala (LA) contains recurrent microcircuits and that these may reverberate. Additionally this reverberant activity is precisely timed with latencies that would facilitate coincidence detection between cortical and sub cortical afferents to the LA. Thus, recent data at the microcircuit level in the amygdala provide some physiological evidence in support of the second Hebbian postulate

Topics: pavlovian, polysynaptic, autoassociative, Ensembles, Expression, Hebb, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571
Publisher: Frontiers Media S.A.
Year: 2009
DOI identifier: 10.3389/neuro.01.027.2009/full
OAI identifier: oai:doaj.org/article:3f39f366abd34d12a20f672853c80017
Journal:
Download PDF:
Sorry, we are unable to provide the full text but you may find it at the following location(s):
  • https://doaj.org/toc/1662-453X (external link)
  • http://journal.frontiersin.org... (external link)
  • https://doaj.org/article/3f39f... (external link)
  • Suggested articles


    To submit an update or takedown request for this paper, please submit an Update/Correction/Removal Request.