Skip to main content
Article thumbnail
Location of Repository

Electrochemical Interrogation of Interactions between

By Surface-confined Dna, Methylene Blue, Dun Pan, Xiaolei Zuo, Ying Wan, Lihua Wang, Jiong Zhang, Shiping Song and Chunhai Fan


Abstract: In this work, we reported a systematic investigation on the interactions between methylene blue (MB) and surface-confined DNA by using electrochemical methods. We demonstrated that the redox potential of MB and binding and dissociation kinetics of MB to DNA differed significantly for single-stranded DNA (ss-DNA) and double-stranded DNA (ds-DNA) immobilized on gold electrodes. This was possibly due to the different binding mechanism between MB and ss- or ds-DNA. This work might provide useful information for developing MB-based sequence-specific electrochemical DNA sensors

Topics: Electrochemical DNA sensors, methylene blue, electrochemical indicators
Year: 2014
OAI identifier: oai:CiteSeerX.psu:
Provided by: CiteSeerX
Download PDF:
Sorry, we are unable to provide the full text but you may find it at the following location(s):
  • (external link)
  • (external link)
  • Suggested articles

    To submit an update or takedown request for this paper, please submit an Update/Correction/Removal Request.