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Kikuchi Disease Caused Intense Cervical Lymph Nodes FDG Uptake in a Patient with Cholangiocarcinoma

By Shih-hsin Chen, Wen-yu Chuang, Ting-jung Wu and Tzu-chen Yen


FDG-PET scan is useful in the evaluation of cholangiocarcinoma. However it is known that FDG uptake is non-specific, and false-positive results might affect clinical judgment if not identified. We described a 36-yearold female referred for FDG-PET evaluation of the cholangiocarcinoma. There was no FDG uptake in the main tumor lesion, but intense uptake was seen in bilateral neck and axillary regions. Neck lymph node biopsy was performed to exclude metastasis. The diagnosis was histiocytic necrotizing lymphadenitis, namely Kikuchi disease. This disease is a benign, self-limiting lymphadenopathy, and could cause intense FDG uptake involving the neck and axillary regions, as demonstrated in this case. When FDG-PET scan reveals unusual metastatic patterns for the tumor biology, biopsy confirmation is necessary for accurate staging

Topics: Ann Nucl Med Sci 2010, 23, 221-225
Year: 2014
OAI identifier: oai:CiteSeerX.psu:
Provided by: CiteSeerX
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