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Stereoselective synthesis of ophiocerin B

By Bhasker Akkala and Krishna Damera


A stereoselective total synthesis of ophiocerin B is reported by asymmetric synthesis, starting from L-malic acid. Of the three stereogenic centers, the vic-diols C-3, C-4 were obtained by Sharpless asymmetric dihydroxylation

Topics: Stereoselective, asymmetric synthesis, Sharpless asymmetric dihydroxylation
Year: 2014
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