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The PLoS Medicine Debate Time To Move from Presumptive Malaria Treatment to Laboratory-Confirmed Diagnosis and Treatment in African

By Children Fever, Christian Lengeler, Hassan Mshinda, Deo Mtasiwa, Marcel Tanner and Blaise Genton


that all fever episodes in African children be treated presumptively with antimalarial drugs. But declining malarial transmission in parts of sub-Saharan Africa, declining proportions of fevers due to malaria, and the availability of rapid diagnostic tests mean it may be time for this policy to change. This debate examines whether enough evidence exists to support abandoning presumptive treatment and whether African health systems have the capacity to support a shift toward laboratory-confirmed rather than presumptive diagnosis and treatment of malaria in children under five. In this Viewpoint, Blaise Genton and colleagues argue in favor of abandoning presumptive treatment for under-fives. Mike English and colleagues present the opposing Viewpoint in a related article

Year: 2013
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