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2 Joint Centers for Systems Biology, 3 Columbia Initiative in Systems Biology,

By Celine Lefebvre, Presha Rajbh, Mariano J. Alvarez, Pradeep B, Keat Lim, Mai Sato, Kai Wang, Pavel Sumazin, Manjunath Kustagi, Brygida C, Katia Basso, Pedro Beltrao, Nevan Krogan, Jean Gautier, Riccardo Dalla and Andrea Califano

Abstract

which the posterior probability of a specific interaction is computed using the prior of that class of interactions and the product of the Likelihood Ratio (LR) of the individual clues supporting it. Computing priors and likelihoods requires large datasets of both positive and negative examples (i.e. interactions that are respectively known to exist and not to exist). These are called Gol

Year: 2013
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