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CD34 + cells mobilized by granulocyte colony-stimulating factor ameliorate radiation-induced liver damage in mice Ning Li 1 † , Li Zhang 2 † , Huixiang Li 1, Baijun Fang 1* Introduction: On the basis of the recently recognized potential of hematopoietic stem cells (HSCs) to give rise to hepatocytes, we have assessed the potential of granulocyte colony-stimulating factor (G-CSF)-mobilized bone marrow-derived CD34 + HSCs to contribute to faster recovery and promote regeneration process after acute liver injury by radiation. Methods: G-CSF-mobilized CD34 + HSCs (1 × 10 5 cells per mouse) were injected via tail vein in the irradiated fema

Year: 2013
OAI identifier: oai:CiteSeerX.psu:10.1.1.352.393
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