The non-decoupling effects of heavy Higgs bosons as well as fermions on the loop-induced H ± W ∓ Z 0 vertex are discussed in the general two Higgs doublet model. The decay width of the process H + → W + Z 0 is calculated at one-loop level and the possibility of its enhancement is explored both analytically and numerically. We find that the novel enhancement of the decay width can be realized by the Higgs non-decoupling effects with large mass-splitting between the charged Higgs boson and the CP-odd one. This is due to the large breakdown of the custodial SU(2)V invariance in the Higgs sector. The branching ratio can amount to 10 −2 ∼ 10 −1 for mH ± = 300 GeV within the constraint from the present experimental data. Hence this mode may be detectable at LHC or future e + e − linear colliders
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