versus gallbladder bile composition: in vivo transport physiology of the gallbladder in rainbow trout. Am J Physiol Regulatory Integrative Comp Physiol 278: R1674–R1684, 2000.—Ion and water transport across the teleost Oncorhynchus mykiss gallbladder were studied in vivo by comparing flow and composition of hepatic bile, collected by chronic catheter, to volume and composition of terminally collected gallbladder bile. Differences in composition were comparable with those of other vertebrates, whereas bile flow (75 µl·kg�1·h�1) was below values reported for endothermic vertebrates. The gallbladder concentrates bile acids five- to sevenfold and exhibits higher net Cl � than Na � transport in vivo, in contrast to the 1:1 transport ratio from gallbladders under saline/saline conditions. Transepithelial potential (TEP) in the presence of bile, at the apical surface, was �13 mV (bil
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