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Lentiviral LTR-directed Expression, Sequence Variation, and Disease Pathogenesis Reviews

By Fred C. Krebs, Tricia H. Hogan, Shane Quiterio, Suzanne Gartner and Brian Wigdahl


The Lentivirus genus, itself a subset of the Retroviridae family of RNA viruses, includes viruses that share a common replicative cycle, which is regulated by key events throughout the cycle. One such event in the viral life cycle is the expression of the viral genome regulated by the activity of the long terminal repeat (LTR). The LTR serves as a convergence point for transcription factors and elements o

Year: 2013
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