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henselae Antibodies after Cat Bite 1

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Abstract

is the causative agent of cat-scratch disease, which is the most common form of human bartonellosis (1). In immunocompromised patients, e.g., HIV-infected patients, B. henselae can give rise to longstanding fever, bacillary angiomatosis, and peliosis hepatitis (2). Domestic cats are the reservoir for B. henselae, and cat fleas transmit the organism between cats (3). The seroprevalence and culture findings of Bartonella spp. in cats have been shown to be low in Sweden (4,5) compared with warmer areas (6). Catscratch disease is most often spread from cats to humans by scratches, but other forms of transmission, including cat bites, have been suggested (7). To determine seroprevalence of antibodies against B. henselae in Sweden, we used data from a recently published prospective study of patients with infected cat bites (8). In addition to the information about bites, information about cat scratches was collected by retrospective review of the patients ’ medical records. Serum samples were taken during the patient’s first visit to a hospital and at a follow-up visit about 2 weeks later. The study was approved by the local ethics committee. Immunoglobulin G against specific Bartonella spp. was detected by the immunofluorescence antibody test (1). Cell-cultivated antigens were prepared from the following strains: B

Year: 2013
OAI identifier: oai:CiteSeerX.psu:10.1.1.306.4372
Provided by: CiteSeerX
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