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Information Theory and Population Genetics

By Reginald D. Smith


The key findings of classical population genetics are derived using a framework based on information theory using the entropies of the allele frequency distribution as a basis. The common results for drift, mutation, selection, and gene flow will be rewritten both in terms of information theoretic measurements and used to draw the classic conclusions for balance conditions and common features of one locus dynamics. Linkage disequilibrium will also be discussed including the relationship between mutual information and r^2 and a simple model of hitchhiking.Comment: 29 pages, 11 figure

Topics: Quantitative Biology - Populations and Evolution, Computer Science - Information Theory
Year: 2012
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