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13 EVALUATION OF DNA INTRAMOLECULAR INTERACTIONS FOR NUCLEOSOME POSITIONING IN YEAST

By Michael Fernandez, Hidetoshi Kono, Satoshi Fujii and Akinori Sarai

Abstract

We calculated intramolecular interaction energies of DNA by threading DNA sequences around crystal structures of nucleosomes. The strength of the intramolecular energy oscillations at frequency ~10 bps for dinucleotides was in agreement with previous nucleosome models. The intramolecular energy calculated along yeast genome positively correlated with nucleosome positioning experimentally measured

Topics: chromatin, histone, indirect readout energy
Year: 2011
OAI identifier: oai:CiteSeerX.psu:10.1.1.193.100
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