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Dissociable Roles of Mid-Dorsolateral Prefrontal and Anterior Inferotemporal Cortex in Visual Working Memory

By Michael Petrides

Abstract

ral prefrontal region yield a very severe impairment. Key words: dorsolateral prefrontal cortex; inferotemporal cortex; visual working memory; monkey; lesions; monitoring; control process There is considerable evidence from f unctional neuroimaging in human subjects (for review, see Owen, 1997; D'Esposito et al., 1998; Petrides, 2000) and studies of monkeys with lesions limited to the mid-dorsolateral (MDL) prefrontal cortex (Petrides, 1991, 1995) that this region is involved in visual working memory. But what precisely is the nature of the involvement of the middorsolateral prefrontal cortex in visual working memory? Does this cortical region play a primary role in the maintenance of information in working memory or is it involved in the executive process of keeping track (i.e., monitoring) of multiple events in working memory? It has been argued (Petrides, 1991, 1994) that the role of the mid-dorsolateral prefrontal cortex lies in the executive process of monitoring information i

Year: 2000
OAI identifier: oai:CiteSeerX.psu:10.1.1.19.3508
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