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The function anovaint performs a one-factorial ANOVA for objects of class “marrayRaw ” or “marrayNorm”. The predictor variable is the average logged intensity of both channels A=0.5*(log2(Ch1)+log2(C Ch1,Ch2 are the fluorescence intensities of channel 1 and channel 2, respectively. The response variable is the logged fold-change M=(log2(Ch2)-log2(Ch1)). The A-scale is divided in N intervals generating N levels of factor A. Note that N should divide the total number of spots approx. equally. The null hypothesis is the equality of mean(M) of the different levels (intervals). The model formula used is M ∼ (A − 1) (without an intercept term)

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Year: 2010
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