Advanced Practice Pharmacists: cost of medications prescribed by ClinicaL Pharmacist PractitionErs compared to Primary Care Providers in North Carolina (APPLE-NC)
Introduction: There is a need to discover new methods of cost-‐effective care
as the healthcare system transitions to a model emphasizing quality outcomes.
Medication prices continue to rise and must be considered when evaluating the
cost of new approaches to treatment. Increased utilization of advanced
practice pharmacists represents one solution to appropriate medication use in
chronic disease state management. However, the effect on the cost of
prescribed pharmacotherapy is unknown. Objective: To determine the cost of
medications prescribed to patients receiving care from both Clinical
Pharmacist Practitioners (CPPs) and Primary Care Providers (PCP: physician,
family nurse practitioner, and physician assistant) compared to those just
receiving care from PCPs. Methods: This was a retrospective matched cohort
analysis. Each cohort was matched by gender, age, and disease states of
interest. There were 130 patients total, 65 in each cohort, seen at the
University of North Carolina outpatient clinics between November 2008 and
November 2011. The primary endpoint was average medication cost per day per
patient determined by the average wholesale price (AWP) of prescribed
medications. The secondary endpoint was average number of therapy changes per
year per patient. Results: There was no statistical difference in the average
medication cost per day per patient in the CPP cohort versus PCP cohort
(38.52vs.38.23, respectively; p = 0.97). Patients managed by CPPs
experienced a higher average number of therapy changes per year compared to
patients only managed by PCPs (21.1 vs. 15.5, respectively; p = 0.032).
Conclusions: CPPs utilized within the healthcare team did not result in an
increased medication cost despite being correlated with more therapy changes.Doctor of Pharmac
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