Analysis of Parkinson's disease brain-derived DNA for alpha-synuclein coding somatic mutations.
Abstract
Although alpha-synuclein (SNCA) is crucial to the pathogenesis of Parkinson's disease (PD) and dementia with Lewy bodies (DLB), mutations in the gene appear to be rare. We have recently hypothesized that somatic mutations in early development could contribute to PDSimilar works
This paper was published in UCL Discovery.
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