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Internalized TSH receptors en route to the TGN induce local Gs-protein signaling and gene transcription

By Amod Godbole, Sandra Lyga, Martin J. Lohse and Davide Calebiro

Abstract

Recent investigations suggest that G-protein-coupled receptors (GPCRs) can signal during intracellular trafficking. Here the authors use fluorescence microscopy approaches to directly visualize and investigate functional consequences of GPCR-mediated signaling at the Golgi/trans-Golgi network

Topics: Science, Q
Publisher: Nature Publishing Group
Year: 2017
DOI identifier: 10.1038/s41467-017-00357-2
OAI identifier: oai:doaj.org/article:8ee231b9e93341b580c3ed939e4beee3
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