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Patiromer Acetate Induced Hypercalcemia: An Unreported Adverse Effect

By Shreeyukta Bhattarai, Stephen Pupillo, Gulshan Man Singh Dangol and Erdal Sarac


Hyperkalemia, a potential life threating condition, is a commonly encountered problem in chronic kidney disease (CKD) patients. Patiromer acetate, a nonabsorbable cation exchange polymer, is a gastrointestinal agent for chronic therapy in patients with persistent hyperkalemia. Patiromer is generally well tolerated in patients; common side effects are gastrointestinal, such as diarrhea, constipation, flatulence, and vomiting. Hypercalcemia, although a theoretical possibility, has not been reported in any major clinical trials. We present a case of hypercalcemia associated with patiromer acetate used for treatment of hyperkalemia in a stage IV CKD patient. Clinicians should be aware of the possibility of hypercalcemia while taking patiromer

Topics: Diseases of the genitourinary system. Urology, RC870-923
Publisher: Hindawi Limited
Year: 2019
DOI identifier: 10.1155/2019/3507407
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