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Immune responses to Epstein–Barr virus: molecular interactions in the virus evasion of CD8+ T cell immunity

By Martin Rowe and Jianmin Zuo

Abstract

Persistent viruses have mechanisms for modulating the host immune responses that are essential for achieving a lifelong virus–host balance while minimizing the viral pathogenicity. Here we review some of the immune-modulating mechanisms evolved by the ubiquitous but potentially oncogenic Epstein–Barr virus, with particular emphasis on the molecular mechanisms of genes interfering with HLA class I antigen presentatio

Topics: R Medicine (General)
Year: 2010
DOI identifier: 10.1016/j.micinf.2009.12.001
OAI identifier: oai:eprints.bham.ac.uk:309
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