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Study on EEG characteristics and etiology of patients with refractory epilepsy

By 童晓欣, 易黎, 林馥英 and 毛立军

Abstract

目的:探讨难治性癫癎的脑电图(EEG)特点与病因.方法:对78例难治性癫癎患者的常规EEG和头颅磁共振成像(MRI)检查资料进行分析.结果:EEG上癎波检出率仅为28%,慢波异常率则高达68%.其中不同发病年龄组(<14岁和≥15岁)和不同病程组(<10年和≥10年)的癎样波检出率和慢波异常率比较,差异均有极显著意义(P<0.0001).而不同发作类型组、头MRI(-)和头MRI(+)组的癎样波检出率和慢波异常率比较,差异无显著意义(P<0.05).借助头颅MRI检查,发现难治性病因主要是大脑发育不全、脑外伤和海马硬化等.结论:难治性癫痢的EEG以慢波异常增多,癎样放电减少为特点,并且与发病年龄、病程长短有着密切关系.故常规EEG检查价值不大,应行Video-EEG监测和MRI检查,以便尽早发现致癎源和难治性病因.0285-871

Topics: 难治性癫痢, 脑电图, 病因, 头颅磁共振成像
Publisher: 临床神经电生理学杂志
Year: 2004
DOI identifier: 10.3969/j.issn.1674-8972.2004.02.007
OAI identifier: oai:localhost:20.500.11897/57225
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