Acidosis potentiates endothelium-dependent vasorelaxation and gap junction communication in the superior mesenteric artery.

Mohanty, Ipsita; Parija, Subas Chandra; Suklabaidya, Sujit; Rattan, Satish

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oai:jdc.jefferson.edu:gastro_hepfp-1049

Acidosis potentiates endothelium-dependent vasorelaxation and gap junction communication in the superior mesenteric artery.

Authors: Ipsita Mohanty
Subas Chandra Parija
Sujit Suklabaidya
Satish Rattan
Publication date: 7 March 2018
Publisher: Jefferson Digital Commons
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Abstract

Extracellular pH is an important physiological determinant of vascular tone that is normally maintained within 7.35-7.45. Any change outside this range leads to severe pathological repercussions. We investigated the unknown effects of extracellular acidosis on relaxation in the superior mesenteric artery (SMA) of goat. SMA rings were employed to maintain isometric contractions at extracellular pH (p

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Last time updated on 20/04/2018

This paper was published in Jefferson Digital Commons.

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