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Efficacy of 5mer4 in combination with HBsAg.

By Ami Patel (139999), Jessica C. Dong (140003), Brett Trost (140006), Jason S. Richardson (140010), Sarah Tohme (140013), Shawn Babiuk (140018), Anthony Kusalik (140024), Sam K. P. Kung (138502) and Gary P. Kobinger (49841)


<p>Exogenous 5mer4 (50 µg) was combined with a commercial Hepatitis B vaccine (Engerix-B, 1 µg). Control mice received the commercial vaccines without 5mer4. Serum was collected from vaccinated animals at 2 •, 4 ▪, 6 ▴, and 8 ▾ weeks post-immunization and evaluated in two-fold dilutions for detection by ELISA. Antibody levels were detected at OD450 nm. (a) Anti-HBsAg antibodies following vaccination with Engerix-B + 5mer4. (b) Anti-HBsAg antibodies following vaccination with Engerix-B alone. Inset displays the data within a more narrow y-axis range. The data represents the arithmetic mean titre ± SEM.</p

Topics: Biochemistry, Microbiology, Immunology, 5mer4
Year: 2012
DOI identifier: 10.1371/journal.pone.0043802.g004
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Provided by: FigShare
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