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Metaplastic Carcinoma of the Left Breast with Extensive Chondroid Differentiation

By Dhiraj B Nikumbh, Sunil V Jagtap, Sujata R Kanetkar, Gaurav Jain and Ashish Bohra


Metaplastic breast carcinoma is very rare neoplasm which contains mixture of carcinomatous (epithelial) and sarcomatous (mesenchymal) elements in variable proportion. Metaplastic carcinoma with chondroid differentiation is even rarer. We report a case of metaplastic carcinoma with extensive chondroid differentiation as there is paucity of information regarding pathological features and clinical outcomes for these rare tumors. Tumor had characteristic definite areas of classic infiltrating duct carcinoma with abundant chondromyxoid matrix, focal areas of chondrosarcoma and cartilagenous metaplasia. Tumour cells were immunoreactive for S-100, ER, and PR. When pathologist encounter breast tumor with chondroid differentiation, careful gross sampling, histopathology and immunoreactivity for mesenchymal and epithelial component are most useful to differentiate metaplastic carcinoma from malignant phylloides tumors and malignant adenomyoepithelioma

Topics: Online Journal of Health and Allied Sciences
Publisher: BS Kakkilaya
Year: 2011
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    1. An immunohitochemical study of metaplastic spindle cell carcinoma, phyllodes tumour and fibromatosis of breast.
    2. Carcinoma with metaplasia.In :Rosen PP,editor.Rosens Breast Pathology. 2nd edition.
    3. (1992). Classification of Metaplastic Carcinoma of breast.
    4. (2003). Corneli ssc CJ, Schnitt SJ et al. Tumour of breast. Invasive Breast Carcinoma.
    5. (2006). Metaplastic Breast Carcinoma with Osseous Differentiation: A Case Report
    6. Metaplastic breast carcinoma: Rare form of mammary cancer.
    7. Metaplastic Carcinoma of the breast : Mammographic and sonographic findings.
    8. Metaplastic carcinoma of the breast clinical presentation treatment result and prognostic factors. Acta Onchologica.
    9. (1989). Metaplastic carcinoma of the breast. I. Matrix producing carcinoma. Hum Pathol
    10. (1999). Papillary lesions.In :Tavassoli FA,editor.Pathology of Breast. 2nd edition. Stanford (CT): Appleton and Lange.

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