Ne-melanomski tumori i predtumorske promjene u periodu od 1996. - 2002. Godine

Abstract

Non-melanoma skin cancers and precancerous skin lesions have a significant morbidity although with relatively low mortality rates in geriatric population. These lesions developed especially on every day sun exposed skin regions. The aim of this study was to determine the prevalence, age and sex distribution of non-melanoma skin cancers and precancerous skin lesions among biopsy specimens collected during seven years (1996-2002) in the University Department of Pathology "Ljudevit Jurak". Also is analyzed their relationship with sun exposure on different body regions. During observed period there were2486 basal cell carcinoma, 419 squamous cell carcinoma and 468 precancerous skin lesions. Basal cell carcinoma was more common in males then in females with ratio 1:0,9 as well as squamous cell carcinoma with male to female ratio 1:0,8. Precancerous skin lesions were more frequent in the female population with male to female ratio 1:1,3. Maximal incidence for booth types of non-melanoma tumours was between 7and 79 years in both sexes while precancerous skin lesions appeared one-decade earlier. Also is found that analyzed skin lesions appear in 60-70% on skin of the head, which is almost permanently sun exposed body region.Nemelanomski tumori kože i predtumorske kožne promjene imaju značajan pobol iako uz nisku smrtnost u pacijenata treće životne dobi. Ove promjene se posebno razvijaju na dijelovima kože koji su svakodnevno izloženi suncu. Cilj ovog rada je prikazati učestalost, razdiobu po spolu i dobi nemelanomskih kožnih tumora i predtumorskih kožnih promjena u bioptičkom materijalu sedmogodišnjeg razdoblja (1996-2002) na Zavodu za Patologiju "Ljudevit Jurak". Također je proučavan odnos kožnih promjena i izloženosti različitih dijelova tijela suncu. U proučavanom periodu bilo je 2486 karcinoma bazalnih stanica, 419 karcinoma pločastih stanica i 468 predtumorskih kožnih promjena. Karcinom bazalnih stanica češće je bio prisutan u muškaraca nego u žena s omjerom 1:0.9 kao i karcinom pločastih stanica s omjerom 1:0,8. Predtumorske kožne lezije bile su češće prisutne kod žena, omjer muškaraca prema ženama bio je 1:1,3. Najveća učestalost za oba nemelanomska kožna tumora bila je između 70 i 79godina starosti u oba spola dok se predtumorske promjene nalaze desetljeće ranije. Proučavane kožne promjene u 60-70% nađene su na koži glave koja je skoro stalno suncu izloženo područje tijela