A novel Monte Carlo technique of simulation of spatial fluorescence distribution
within the human skin is presented. The computational model of skin takes into
account the spatial distribution of fluorophores, which would arise due to the
structure of collagen fibres, compared to the epidermis and stratum corneum
where the distribution of fluorophores is assumed to be homogeneous. The results
of simulation suggest that distribution of auto-fluorescence is significantly
suppressed in the near-infrared spectral region, whereas the spatial
distribution of fluorescence sources within a sensor layer embedded in the
epidermis is localized at an ‘effective’ d
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