research article review journal article
Interleukin-6: An osteotropic factor influencing bone formation?
Abstract
peer reviewedInterleukin (IL)-6 has long been considered as an osteoresorptive factor. However, recent data indicate that IL-6 could influence bone formation in conditions of increased bone turnover. In this paper, the effects of IL-6 and its soluble receptor on osteoblast proliferation, differentiation and apoptosis are readdressed. A brief summary of IL-6 signaling after binding to its receptor is provided and hypotheses concerning IL-6 and the central control of bone formation are also highlighted. (c) 2005 Elsevier Inc. All rights reserved- journal article
- http://purl.org/coar/resource_type/c_6501
- info:eu-repo/semantics/article
- peer reviewed
- interleukin-6
- Bone formation
- Bone Resorption/physiopathology
- Cell Differentiation
- Cell Proliferation
- Humans
- Interleukin-6/physiology
- Leptin/physiology
- Osteoblasts/cytology/pathology/physiology
- Osteogenesis/physiology
- Receptors, Interleukin-6/physiology
- Signal Transduction
- Human health sciences
- Endocrinology, metabolism & nutrition
- Sciences de la santé humaine
- Endocrinologie, métabolisme & nutrition
Similar works
Full text
Last time updated on 20/08/2013
This paper was published in Open Repository and Bibliography - Liège.
Having an issue?
Is data on this page outdated, violates copyrights or anything else? Report the problem now and we will take corresponding actions after reviewing your request.