Skip to main content
Article thumbnail
Location of Repository

Cartilaginous melanoma: case report and review of the literature Melanoma cartilagíneo: caso clínico e revisão da literatura

By Parente Joana Devesa, José Manuel Pereira da Silva Labareda, Elvira Augusta Felgueira Leonardo Fernandes Bártolo, Maria Fernanda Sachse Pinto Fonseca Santos and Esmeralda Maria Seco do Vale

Abstract

Malignant melanoma can present a variety of histopathological patterns. Cartilaginous change in the absence of osteogenic differentiation is extremely rare in malignant melanoma, being among the least frequent of the wide range of melanoma histologic patterns. We report a case of a 47-year-old woman with a subungual nodule on her right great toe for many years. Histopathological examination of the lesion led to a diagnosis of malignant melanoma with cartilaginous differentiation devoid of concomitant osseous areas. It would appear that this unusual form of melanoma has a predilection for acral location, particularly the subungual region. Malignant melanoma with chondroid stroma should therefore be considered in the differential diagnosis of cartilaginous lesions of the toes and fingers. Careful examination of the overlying epidermis and identification of an in situ component of melanoma may be necessary in order to establish the correct diagnosis.<br>O melanoma maligno pode apresentar uma grande variedade de padr&#245;es histopatol&#243;gicos. A presen&#231;a de diferencia&#231;&#227;o cartilag&#237;nea, na aus&#234;ncia de diferencia&#231;&#227;o osteog&#233;nica, &#233; extremamente rara no melanoma maligno. O melanoma cartilag&#237;neo est&#225; entre os padr&#245;es histol&#243;gicos menos frequentes. Relatamos um caso de uma doente do sexo feminino de 47 anos de idade com um n&#243;dulo subungueal no 1&#186; dedo do p&#233; direito com muitos anos de evolu&#231;&#227;o. O exame histopatol&#243;gico da les&#227;o revelou melanoma cartilag&#237;neo, sem &#225;reas de diferencia&#231;&#227;o osteog&#233;nica. Esta variante de melanoma parece ter predile&#231;&#227;o pela extremidades, sobretudo pela regi&#227;o subungueal. Assim, o melanoma maligno com diferencia&#231;&#227;o condr&#243;ide, deve ser tido em considera&#231;&#227;o no diagn&#243;stico diferencial de les&#245;es acrais cartilag&#237;neas. A observa&#231;&#227;o cuidadosa da epiderme e a identifica&#231;&#227;o de um componente do melanoma in situ podem ser necess&#225;rios para estabelecer um diagn&#243;stico correto

Topics: Cartilagem, Dedos do pé, Melanoma, Cartilage, Melanoma, Toes, Dermatology, RL1-803, Medicine, R, DOAJ:Dermatology, DOAJ:Medicine (General), DOAJ:Health Sciences
Publisher: Sociedade Brasileira de Dermatologia
Year: 2013
OAI identifier: oai:doaj.org/article:79e2de058d6b49e385c88de2e14f4b96
Journal:
Download PDF:
Sorry, we are unable to provide the full text but you may find it at the following location(s):
  • https://doaj.org/toc/1806-4841 (external link)
  • https://doaj.org/toc/0365-0596 (external link)
  • http://www.scielo.br/scielo.ph... (external link)
  • https://doaj.org/article/79e2d... (external link)
  • Suggested articles


    To submit an update or takedown request for this paper, please submit an Update/Correction/Removal Request.