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Relationship between depression and the factors related to senile patients with hypertension

By Jian-mei ZHOU, En-yan YU, Ai-hua REN and Li-yue ZHU

Abstract

Objective To study the relationship between depression and the factors related to senile patients with hypertension.Methods From Oct.2009 to Oct.2010,129 patients(over 80 years of age) with hypertension under the care of Zhejiang Hospital were divided into simple hypertension group(n=63) and depression hypertension group(n=66) according to whether or not there was symptoms of depression.The platelet activation ratio(CD42a+/CD14+),fibrinogen(Fib),urinary albumin creatinine ratio(ACR),homocysteine(Hcy),C-reactive protein(CRP),standard deviation of normal to normal intervals in 24 hours(SDNN),standard deviation of average normal to normal intervals in 24 hours(SDANN) and other related factors were compared between the two groups.Results The baseline data of blood glucose,creatinine and blood lipids showed no significant statistical difference between two groups(P > 0.05);CD42a+/CD14+,Fib,ACR,Hcy and CRP were significantly higher,but SDNN and SDANN were significantly lower in depression group than in simple group(P < 0.01).Conclusion There exists significant relationship between depression and the factors related to senile patients with hypertension,so the clinicians should pay more attention to the depression factor in senile hypertension patients

Topics: aged,80 and over; hypertension; depression, Medicine (General), R5-920, Medicine, R, DOAJ:Medicine (General), DOAJ:Health Sciences
Publisher: Editorial Board of Medical Journal of Chinese People's Liberation Army
Year: 2011
OAI identifier: oai:doaj.org/article:ca7d23c1c0784faea9fec279f2ef812f
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