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Brain SPECT imaging in Huntington's disease before and after therapy with olanzapine: case report

By ETCHEBEHERE ELBA C. S. C., LIMA MARIANA C. L., PASSOS WALMIR, MACIEL JR JAIME A., SANTOS ALLAN O., RAMOS CELSO DARÍO and CAMARGO EDWALDO E.

Abstract

Olanzapine, an atypical antipsychotic drug, was administered to a patient with Huntington's disease (HD) with marked choreiform movements. Brain SPECT with 99mTc-HMPAO was performed before and after treatment. Brain SPECT imaging has been performed in patients with HD in order to determine the status of basal ganglia perfusion. The use of brain SPECT with 99mTc-HMPAO before and after treatment in patients with HD has not been yet reported. The marked hypoperfusion of the basal ganglia on brain SPECT performed before therapy with olanzapine improved significantly after treatment

Topics: Huntington's disease, brain SPECT, olanzapine, basal ganglia, 99mTc-HMPAO, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571, Internal medicine, RC31-1245, Medicine, R, DOAJ:Neurology, DOAJ:Medicine (General), DOAJ:Health Sciences
Publisher: Academia Brasileira de Neurologia (ABNEURO)
Year: 1999
OAI identifier: oai:doaj.org/article:3e0b6ba9da894af8856b078c20687776
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