Humanized mice for modeling human infectious disease: challenges, progress, and outlook.

Legrand, Nicolas; Ploss, Alexander; BALLING, Rudi; Becker, Pablo D.; Borsotti, Chiara; Brezillon, Nicolas; Debarry, Jennifer; de Jong, Ype; Deng, Hongkui; Di Santo, James P.; Eisenbarth, Stephanie; Eynon, Elizabeth; Flavell, Richard A.; Guzman, Carlos A.; Huntington, Nicholas D.; Kremsdorf, Dina; Manns, Michael P.; Manz, Markus G.; Mention, Jean-Jacques; Ott, Michael; Rathinam, Chozhavendan; Rice, Charles M.; Rongvaux, Anthony; Stevens, Sean; Spits, Hergen; Strick-Marchand, Helene; Takizawa, Hitoshi; van Lent, Anja U.; Wang, Chengyan; Weijer, Kees; Willinger, Tim; Ziegler, Patrick

research article review journal article

oai:orbilu.uni.lu:10993/2686

Humanized mice for modeling human infectious disease: challenges, progress, and outlook.

Abstract

peer reviewedOver 800 million people worldwide are infected with hepatitis viruses, human immunodeficiency virus (HIV), and malaria, resulting in more than 5 million deaths annually. Here we discuss the potential and challenges of humanized mouse models for developing effective and affordable therapies and vaccines, which are desperately needed to combat these diseases

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Open Repository and Bibliography - Luxembourg

oai:orbilu.uni.lu:10993/2686

Last time updated on 16/07/2013

This paper was published in Open Repository and Bibliography - Luxembourg.

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