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Totally drug-resistant and extremely drug-resistant tuberculosis: the same disease?

By Giovanni Battista Migliori, Rosella Centis, Lia D'Ambrosio, Antonio Spanevello, Emanuele Borroni, Daniela Maria Cirillo and Giovanni Sotgiu


The emergence of totally drug-resistant (TDR) tuberculosis in India and Iran has been recently discussed in the literature. The 15 TDR tuberculosis cases previously described in Iran were cited as resistant to “all first-line drugs (FLDs) and second-line drugs (SLDs)” [1, 2]. The 4 Mumbai cases were resistant to all FLDs (isoniazid, rifampicin, ethambutol, pyrazinamide, streptomycin) and SLDs tested (ofloxacin, moxifloxacin, kanamycin, amikacin, capreomycin, para-aminosalicylic acid, ethionamide)

Publisher: University of Chicago Press
Year: 2012
DOI identifier: 10.1093/cid/cis128
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Provided by: UnissResearch
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