Electronic, thermodynamic, and optical characterization of schiff base compound (C11H7IN2O2S)

Total energy optimization, electronic band structure, and thermodynamic and optical properties calculations for a Schiff base molecule (C11H7IN2O2S) have been performed using the first-principles Density functional (DFT) calculations. The electronic properties were investigated using theoretical techniques, revealing a moderate bandgap indicative of semiconducting behavior suitable for optoelectronic applications. The estimated band gap was about 1.85 eV. The calculated HOMO-LUMO energies show that charge transfer is done within the molecule. The thermodynamic analysis provided insights into the stability and thermal behavior of the compound, including parameters such as heat capacity, entropy, and Gibbs free energy, which confirmed its structural robustness under standard conditions. The optical properties were characterized by the dielectric function, refractive index, absorption coefficient, and optical conductivity. The compound exhibited strong absorption in the ultraviolet (UV) region, with a prominent absorption edge near similar to 1.8 eV and significant peaks at similar to 3.5 eV, highlighting its potential as a UV-sensitive material. The refractive index and reflectivity analysis demonstrated its efficient light interaction and propagation properties, while the plasmon energy loss function confirmed energy dissipation peaks in the UV range. These findings position the Schiff base compound as a promising candidate for advanced applications in optoelectronics, UV photodetectors, and energy-efficient photonic devices. The synergistic combination of electronic, thermodynamic, and optical attributes underscores the compound's versatility and utility in emerging technological fields

The effect of music therapy applied to individuals receiving hemodialysis treatment on itching, muscle cramps and comfort

10.07.2025 tarihine kadar kullanımı yazar tarafından kısıtlanmıştır.Bu araştırma, hemodiyaliz tedavisi alan bireylere uygulanan müzik terapisinin bireylerin kaşıntı, kas krampları ve konfor düzeylerine etkisini belirlemek amacıyla yapılmıştır. Tek gruplu ön test ve son test yarı deneysel desendeki bu araştırma, Aralık 2023 – Ocak 2024 tarihleri arasında Amasya ili Sabuncuoğlu Şerefeddin Eğitim ve Araştırma Hastanesi Hemodiyaliz Kliniği'nde tedavi gören, dahil edilme kriterlerine uyan ve araştırmaya katılmayı kabul eden 39 birey ile yürütülmüştür. Bireylere 4 hafta boyunca haftada üç kez ve 30 dakikalık seanslar şeklinde müzik terapi uygulanmıştır. Araştırma verileri Hasta Tanıtım Formu, 5-D Kaşıntı ölçeği, kas krapmı ölçümü için Visual Analog Skalası, Hemodiyaliz Konfor Ölçeği Versiyon II kullanılarak toplanmıştır. Hemodiyaliz tedavisi alan bireylerin 5-D Kaşıntı Ölçeği ön test puan ortalaması 14,41±3,36 iken son test puan ortalaması 10,56±3,24, bireylerin kas krampı ölçümü için Visual Analog Skala ön test puan ortalaması 7,41±2,08 iken son test puan ortalaması 5,48±2,34, bireylerin Hemodiyaliz Konfor Ölçeği Versiyon II ön test puan ortalaması 81,58±9,86 iken son test puan ortalaması 88,69±9,81 bulunmuş olup, müzik terapisinin bireylerin kaşıntı ve kas krampı düzeylerinde azalma, konfor düzeylerinde ise anlamlı bir artış sağladığı saptanmıştır (t=7,526; t=6,681; t=-8,114; p<0,05). Sonuç olarak hemodiyaliz tedavisi alan bireylere uygulanan müzik terapinin bireylerin deneyimlediği kas krampı ve kaşıntı seviyelerinde azalma sağladığı, aynı zamanda bireylerin konfor düzeylerini arttırdığı belirlenmiştir. Hemodiyaliz tedavisi alan bireylerin sık deneyimledikleri semptomlar olan kaşıntı ve kas kramplarının azaltılmasında ve bireylerin konfor düzeylerinin arttırılmasında hemşirelerin müzik terapisini kullanmaları önerilmektedir.This study was conducted to determine the effect of music therapy applied to individuals receiving hemodialysis treatment on itching, muscle cramps and comfort levels of individuals. This study, which has a single-group pre-test and post-test quasi-experimental design, was carried out with 39 individuals who were treated at the Hemodialysis Clinic of Sabuncuoğlu Şerefeddin Training and Research Hospital in Amasya province between December 2023 and January 2024, who met the inclusion criteria and agreed to participate in the study. Music therapy was applied to the individuals three times a week for 4 weeks in the form of 30-minute sessions The research data were collected using the Patient Identification Form, 5-D Itch Scale, Visual Analog Scale (VAS) (muscle cramp measurement), Hemodialysis Comfort Scale Version II. The mean pre-test score of the 5-D Itch Scale was 14.41±3.36 and the mean post-test score was 10.56±3.24, the mean pre-test score of the Visual Analog Scale for muscle cramp measurement was 7.41±2.08 and the mean post-test score was 5.48±2.34, the mean pre-test score of the Hemodialysis Comfort Scale Version II was 81.58±9.86, while the mean post-test score was 88.69±9.81, and it was found that music therapy provided a significant decrease in itching and muscle cramp levels and a significant increase in comfort levels (t=7.526; t=6,681; t=-8,114; p<0.05). As a result, it has been determined that music therapy applied to individuals receiving hemodialysis treatment provides a decrease in the muscle cramp and itching levels experienced by individuals, and at the same time increases the comfort levels of individuals. It is recommended that nurses use music therapy to reduce itching and muscle cramps, which are common symptoms experienced by individuals receiving hemodialysis treatment, and to increase the comfort levels of individuals

Eliminating a gap on child maltreatment in a developing country: A comprehensive web-based training for future counselors

Background: Public personnel working in the fields of education and health are the primary professionals in Turkey responsible for recognizing issues related to child maltreatment. Therefore, it is crucial for them to be knowledgeable about the legal and guidance processes to follow. Objective: This study aims to investigate the effectiveness of a web-based training on child maltreatment (CM) for undergraduate students. The goal was to determine whether the students would gain knowledge and awareness about the signs of child maltreatment, along with a positive attitude towards reporting. Participants and Setting: The sample consisted of 85 counseling candidates (42 received the training and 43 did not). Methods: The study employed a quasi-experimental design with a control group to examine the effectiveness of the program. Pre-test, post-test, and 6-month follow-up data were analyzed using mixed ANOVA. Results: Participants who attended the program showed greater improvement compared to those who did not receive training, although some of these improvements were only partial. Conclusion: Overall, the study demonstrated the effectiveness of a comprehensive web-based program on CM for future counselors, although its effectiveness was partial in some areas. Future research should consider testing programs with different content, using different samples, and investigating programs that can be delivered in shorter time frames

Kadim Çağlardan Günümüze Tedavide Tıbbi ve Aromatik Bitkilerin Rolü

Plants have served humanity for health, food, and other purposes since ancient times. Therefore, medicine and pharmacy have been two professions that are not separated from each other for centuries, when plants were used for therapeutic purposes. There are many written sources about the therapeutic use of plants since prehistoric times. Ensuring the use of the plants used in treatment by passing them through a scientific filter is important in terms of public health. In this review, contributions of the ancient civilizations, particularly in Mesopotamia (e.g., Sumerian, Babillion, Hittite, Greek) as well as Indian, Chinese, Japanese, and Islamic civilizations, are briefly reviewed in the “General Information” section, considering the development process of medicine and herbal therapy.Bitkiler çok eski çağlardan bu yana sağlık, besin ve bazı diğer amaçlarla kullanılarak insanlığa hizmet etmektedir. Dolayısıyla bitkilerin tedavi amacıyla kullanıldığı yüzyıllar boyunca hekimlik ve eczacılık birbirinden ayrılmayan iki meslek olagelmiştir. Tarih öncesi çağlardan itibaren bitkilerin tedavi amacıyla kullanımına dair pek çok yazılı kaynak mevcuttur. Tedavide kullanılan bitkilerin bilimsel süzgeçten geçirilerek kullanımlarının sağlanması toplum sağlığı açısından önem ihtiva etmektedir. Tıbbın ve bitkilerle tedavinin gelişim sürecine bakıldığında, bu derlemede başta Mezopotamya kökenli olmak üzere kadim medeniyetler (Sümer, Babil, Hitit, Yunan, vs) ile Hint, Çin, Japon ve İslam medeniyetlerinin katkıları gözden geçirilmiştir. Bu derleme ile kadim bilgiler gün ışığına çıkartılmış olup, geleneksel bilgilerin modern fitoterapi araştırmalarında kullanılabilmesi için literatüre katkıda bulunulmuştur

The effect of game-based learning on the acquisition of intramuscular injection skills

Aim: This study aims to determine the efficiency of game-based learning in nursing students' IMI skills training. Background: Today, with the unstoppable development of digital technologies, the skills required by modern health services and the needs of nursing students have changed. For this reason, new teaching methods have been researched instead of traditional methods. Game-based learning will choose a dynamic learning environment for the use of game design elements in the acquisition of knowledge and the teaching of psychomotor skills, based on the theory of experimental learning while improving learning experiences with active student participation. However, its use in nursing education is limited. Design: A pretest-posttest randomized controlled experimental study design was used. Methods: The study was conducted at Ege University Faculty of Nursing in western Turkey. The sample size was determined through stratified randomization method and 135 nursing students participated in the study. Data were gathered by questionnaire method with the Student Descriptive Characteristics Form (SDCF), Intramuscular Injection Knowledge Form (IMIKF), Intramuscular Injection Implementation Checklist (IMIIC), Student Satisfaction and Confidence in Learning Scale (SSCLS) and Visual Comparison (Comfort) Scale (VCS). The chi-square test, the Mann-Whitney U test and the Brunner Langer method were performed in the SPSS 25.0 program. Results: After the Intramuscular Injection Game-Based Learning Practice (IMIGBLP), the mean score of IMIICL (61 +/- 4.4) of the intervention group was significantly higher than the mean score of the control group (38 +/- 2.1) (p<0.05). The mean score of the students in the intervention group was determined to be significantly higher than the mean score of the control group (p<0.05). A significant difference was detected between the intervention and control group students in terms of their VCS scores after IMIGBLP (p<0.05). Conclusion: Considering the results of the study, it is recommended to use the game-based learning method in psychomotor skill training in nursing

Relationship Between Core and Respiratory Muscle Endurance in Elite Handball Players

Amaç: Yüksek düzeyde postüral kontrol, kuvvet, aerobik ve solunum kas enduransı gerektiren hent-bolda postüral kontrol ve solunum iş birliği çok önemlidir. Literatürde hentbol oyuncularında solu-num-kor endurans ilişkisini inceleyen çalışmaya rastlanmamıştır. Bu çalışma elit hentbol oyuncuların-da gövde kas dayanıklılığı ile solunum kas fonksiyonu arasındaki ilişkiyi incelemeyi amaçlamaktadır. Materyal ve Metod: Çalışmaya 24 (22.17±3.42 yıl) kadın hentbol oyuncusu dahil edildi. Sporcularda kor endurans, Zorlu Vital Kapasite (FVC), 1. saniyedeki Zorlu Ekspirasyon Hacmi (FEV1), FEV1/FVC, Zirve Ekspiratuar Akım Hızı (PEF)’nı içeren pulmoner fonksiyonlar, solunum kas kuvveti (Maksimal İnspiras-yon Basıncı; MIP, Maksimal Ekspirasyon Basıncı; MEP) ve enduransı değerlendirildi. Bulgular: Baskın ekstremite duvar destekli oturma tutma testi süresi (s) ile solunum kas performansını içeren solunum kası enduransı (cmH2Oxs) (r=0,536) ve süresi (Tmax) (r=0,441), MIP (r=0,446; r=0,439), MEP (r=0,482; r=0,546) (cmH2O/%) arasında pozitif yönde anlamlı ilişki vardı. Baskın olmayan ekstre-mite duvar destekli oturma süresi ile MIP (r=0,534; r=0,548) (cmH2O/%), MEP (r=0,442) (%) arasında pozitif yönde anlamlı ilişki gözlemlendi (p≤0,05). Solunum kas enduransı ve ekspiratuar kas kuvveti değerleri (%53,4, p=0,001; r=0,764) kor kas enduransı üzerinde önemli bir etkiye sahiptir. Sonuç: Hentbol oyuncularında daha iyi postüral kontrol, kuvvet ve dayanıklılık için kor-solunum kası iş birliği içeren antrenmanlar geliştirilmelidir. Postüral stabiliteyi ve solunum fonksiyonunu iyileştirme-ye yönelik kapsamlı bir eğitim programının atletik performansa katkısı araştırılmalıdır.Background: Postural and respiratory control cooperation is crucial in handball, which requires high levels of postural control, strength, aerobic and respiratory endurance. In the literature, no study has been found that examines the relationship between respiratory and core endurance in handball players. This study aims to investigate the correlation between core muscle endurance and respira-tory muscle function in elite handball players. Materials and Methods: Twenty-four female handball players were (22.17±3.42 years) included in the study. Core endurance, pulmonary functions including Forced Vital Capacity (FVC), Forced Expiratory Volume in First Second (FEV1), FEV1/FVC, Peak Expiratory Flow (PEF), respiratory muscle endurance and strength (Maximal Inspiratory Pressure; MIP, Maximal Expiratory Pressure; MEP) were evaluated in players. Results: There were positive significant correlations between dominant wall sit hold test duration (s) and respiratory muscle performance, including respiratory muscle endurance (cmH2Oxs) (r=0.536) and duration (Tmax) (r=0.441), MIP (r=0.446; r=0.439), MEP (r=0.482;r=0.546) (cmH2O/%). The positive significant correlations were observed between non-dominant wall sit hold duration and MIP (r=0.534; r=0.548) (cmH2O/%), MEP (r=0.442) (%) (p≤0.05). The respiratory muscle endurance and expiratory muscle strength values (53.4%, p=0.001; r=0.764) have a significant influence on core muscle endurance. Conclusions: Trainings that include core-respiratory muscle cooperation should be developed for better postural control, strength and endurance in handball players. The contribution of a compre-hensive training program to improve postural stability and respiratory function on athletic perfor-mance should be investigated.[EN] Authors declared no financial support

Integrated disaster management

Until recently, disaster management processes were generally focused on healing wounds. In this approach, emphasis was placed on response and recovery processes (crisis management) after disasters occurred. However, disasters have been experienced, and studies have shown that it is not correct to approach disasters only with a focus on crisis management (response and recovery), but pre-disaster risk reduction (mitigation and preparedness) studies are also very important for disaster resilience. The importance of disaster risk reduction strategies began to be emphasized more in international studies that started with The International Decade for Natural Disaster Reduction (IDNDR 1990-2000) and continued with the Yokohama Strategy (1994). In the ongoing process, the Hyogo Framework for Action (2005-2015) and, most recently, the Sendai Framework for Disaster Risk Reduction (2015-2030) have reiterated the importance of risk management for resilient communities within the framework of lessons learned. Although risk management is considered very important for disaster resilience in new disaster management strategies, it is not sufficient alone for successful disaster management. Preparedness, mitigation, response, and recovery processes, which are all stages of disaster management and risk and crisis management, need to be handled. The disaster management system formed by all these processes is called integrated disaster management. Integrated disaster management is based on the focus on preventing disasters, reducing their damage, and increasing resilience. This disaster management system increases the resilience of individuals, societies, and countries to disasters. © 2025 Nova Science Publishers, Inc. All rights reserved

Sulfur dioxide (SO2) donors, a new gasotransmitter, improve erectile dysfunction after castration in a rat model

Background: Androgen deprivation is associated with erectile dysfunction (ED). In different animal models, sulfur dioxide (SO2) donors Na2SO3 and NaHSO3 reduced oxidative stress, fibrosis, and inflammation which contribute to the pathogenesis of androgen deprivation-induced ED, however the effect of SO2 donors on ED in castrated rats were not known. Objective: To investigate the therapeutic effect of SO2 donors, Na2SO3/NaHSO3, on ED in castrated rat model. Materials and methods: Sprague-Dawley male rats (n = 30) were divided into four groups; control, control-treated with Na2SO3/NaHSO3, castrated, and castrated-treated with Na2SO3/NaHSO3. Castration was induced by bilateral scrotal incisions. Four weeks after castration, rats were treated with Na2SO3/NaHSO3 (0.54/0.18 mmol/kg) intraperitoneally (i.p.) for 4 weeks. Intracavernosal pressure/mean arterial pressure ratio (ICP/MAP) and total ICP were measured to evaluate in vivo erectile responses in cavernosal tissue. In vitro relaxant and contractile responses were measured in all groups. Endothelial nitric oxide synthase (eNOS), neuronal NOS (nNOS), PI3 kinase p85 alpha + gamma (PI3K), protein kinase B (AKT 1/2/3), cysteine dioxygenase-1 (CDO), and aspartate aminotransferase (AAT) expressions and localizations were evaluated by Western blotting and immunohistochemical staining. The smooth muscle/collagen ratio was evaluated by Masson's trichrome staining. Results: Prostate (p 0.05). Discussion and conclusion: SO2 donors significantly improve erectile functions and relaxation responses in a castrated rats via ameliorating endothelial damage and fibrosis. Androgen deprivation inhibits the AKT/eNOS signaling while SO2 activates this pathway. SO2 donors may be promising for the treatment of ED in hypoandrogenic men.Ankara University Scientific Research Projects Coordination Unit; [TDK-2022-2463]This study was supported by the Ankara University Scientific Research Projects Coordination Unit (Project number: TDK-2022-2463) and presented as a part of doctoral thesis

The digital eye for mammography: deep transfer learning and model ensemble based open-source toolkit for mass detection and classification

Breast cancer stands as a prevalent malignancy affecting women globally, and a screening method, mammography, boasts reliability for early diagnosis. Nevertheless, interpretive errors during population screening may result in false negatives and positives. To address this, Computer-Aided Detection systems rooted in deep learning have emerged, aiming to reduce both false positive and negative predictions. This study introduces an open-source toolkit called The Digital Eye for Mammography (DEM) and addressing limitations in mammography screening for mass detection and classification. The DEM comprises 11 state-of-the-art object detection architectures and uses a meticulously labeled dataset. It serves as a transfer learning source, and provides ensemble of models from diverse deep-learning architectures, resulting in a more robust solution. Experiments conducted on widely-used datasets indicate that the DEM outperforms existing transfer learning sources by significant margins in terms of true positive rate (TPR). According to the experimental results, the DEM serves as a better transfer learning source for mass detection in pathology-proven InBreast and CBIS-DDSM datasets, presenting improvements 12% and 5% in TPR performance at 0.1 false positive per image (FPPI), respectively. Compared to literature, the DEM achieves lower FPPI values while maintaining higher sensitivity, indicating its potential usage as a transfer learning source. By employing ensemble strategies, the DEM produces more reliable outcomes in our KETEM dataset, reducing FPPI by 49% for BI-RADS 1-2 (Breast Imaging Reporting and Data System) and 46% for BI-RADS 4-5 compared to the best individual model while preserving TPR values. The DEM's results suggest its ability to attain better performance without requiring complex model hyperparameters optimization. The GitHub repository of the DEM project is publicly available on: https://github.com/ddobvyz/digitaleye-mammography

Values education in distance education according to social studies teachers

2019’da ortaya çıkarak insanların sağlığını ve hatta yaşam tarzını alt üst eden Covid 19 salgını, eğitim anlayışını da kökten değiştirmiştir. Bu sürecin başında hemen hemen tüm ülkelerde okullar geçici olarak tatil edilmiş fakat pandeminin etkisi artınca teknik altyapısı ve uyum sağlama kapasitesi yüksek olan ülkeler eğitimi tamamen uzaktan çevrimiçi hale getirmiştir. Türkiye de bu süreci en hızlı ve en başarılı yürüten ülkelerin başında gelmiştir. Öğretmen ve öğrencilerin bu süreçte internette geçirdiği vaktin birden ve büyük oranda artması, akademik kaygıların ötesinde değer anlamında da bir kaygının oluşmasına enden olmuştur. Zira internetin uçsuz bucaksız sınırsız dünyasında eğitimin verilmeye çalışılması süreci zorlaştırmıştır. Bu nedenle eğitimin tüm seviyelerde uzaktan yapıldığı bu süreçte, akademik amaçların ötesinde değer eğitiminin de aksatılmadan yürütülmesi önemlidir. Bu doğrultuda çalışmanın amacı, öğretmen görüşleri doğrultusunda uzaktan sosyal bilgiler eğitiminde, değerler eğitiminin yerini ve önemini tespit ederek bu konuda yaşanan problemlere çözümler üretebilmektir. Nitel yöntemlerden olgubilim deseninin kullanıldığı bu araştırmanın çalışma grubunu Tokat il genelinde görev yapan 28 sosyal bilgiler öğretmeni oluşturmaktadır. Araştırmacı tarafından hazırlanan yarı yapılandırılmış görüşme formu ile toplanan veriler R tabanlı QDA programıyla betimsel analiz yapılarak çözümlenmiştir. Araştırmadan elde edilen sonuçlara göre değer eğitiminde aile ve okulun çok önemli bir yeri olmakla birlikte, bu konuda yüz yüze eğitimin uzaktan eğitime kıyasla daha etkili olduğu görülmüştür.The Covid 19 epidemic, which emerged in 2019, radically changed the understanding of education. At the beginning of this process, schools were temporarily closed in almost all countries, but as the effect of the pandemic increased, many countries made education online completely remotely. Türkiye is one of the countries that carries out this process most successful way. In this process, where education is carried out remotely at all levels, it is important that values education be carried out uninterruptedly In this direction, the aim of the study is to determine the place and importance of values education in distance social studies education in line with the opinions of teachers and to produce solutions to the problems experienced in this regard. The study group of this research, in which the phenomenology pattern, which is one of the qualitative methods, is used, consists of 28 social studies teachers working throughout the province of Tokat. The data collected by the semi-structured interview form prepared by the researcher were analyzed with the R-based QDA program and descriptive analysis method. According to the results, although family and school have a very important place in values education, it has been seen that face-to-face education is more effective than distance education in this regard