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    River linear inversion to assess drainage base-level fall history in North-western Apennines and implications on the Alessandria Basin tectonic activity

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    Drainage network systems are responsive elements to recent active tectonics from among all the topographic features. In geodynamically active areas, fluvial landscapes can record different processes through the formation and current presence of features related to spatial-temporal variation in base-level fall and vertical incision of stream channels. This study focuses on the tectonic evolution of the Alessandria Basin, a synorogenic tectonic basin located at the junction between the Alps and the Apennines, that experienced progressive subsidence during the overthrusting of the Monferrato Thrust Front (the westernmost outer arc of the Apennine belt) onto the Po Foreland Basin. Even though several studies have assessed the Neogene tectonic evolution at a regional scale, rates and timing of the Quaternary activity are still poorly understood in terms of both Alps/Apennines uplift and activity of the compressive front of the Monferrato Arc. In this paper, we applied the method of the river profile linear inversions to reconstruct the base-level fall history of 6 catchments that drain into the Alessandria Basin. We used nine 10Be-derived basin-average denudation rates to constrain the erodibility parameter needed to infer base-level fall rates from χ-transformed river profiles. The results describe the tectonic history of the area in the last ∼5 Ma, documenting increases in base-level fall rate with an initial peak between 3 and 2.5 Ma, and a second between 2 and 1.5 Ma. While the first peak is coeval with the uplift phase that involved most of the northern-central Apennine, the second one suggests an acceleration in subsidence of the Alessandria Basin concurrently with the uplift of the Monferrato Thrust Front

    CBCT/ExoCT reconstruction software

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    Reconstruction algorithm for cone beam CT with conventional and oscillating scanning orbit Disclaimer This software was developed in Matlab environment (MathWorks Inc) by Antonio Minopoli and Antonio Sarno as part of the PRIN project Q-CT funded by the Italian Ministry of University and Research (CUP E53D23012420006). The activity of Antonio Sarno was also part of the Prof-of-Concept project QE-CBCT funded by the Italian Ministry of the Economic Development (MISE) through the Italian Institute of Nuclear Physics (CUP C18H23000670002). Permission of use is hereby granted, free of charge, to any person obtaining a copy of the Software, to deal in the software without restriction, including without limitation the rights to use, copy, modify, merge, publish, distribute, or sell copies of the Software or derivatives. Developers assume no responsibilities whatsoever for the use by other parties of the software and make no guarantees, expressed or implied, about its quality, reliability, or any other characteristics. Although this software can be redistributed and/or modified freely. Software features The developed software permits analytical FDK reconstruction in CBCT, either by using CPU or GPU architecture. It permits sinogram input either for conventional circular scanning geometry or for oscillating geometry as described in the quoted paper. Instruction for the use This MATLAB project implements the Feldkamp-Davis-Kress (FDK) reconstruction algorithm specifically adapted for cone beam computed tomography (CBCT) with an oscillating scanning orbit. The algorithm is designed to handle the source overlapping introduced by the oscillating orbit, providing accurate 3D reconstructions from cone beam data. It was developed and tested on Matlab R2024a and Windows OS List additional toolboxes required Image Processing Toolbox Parallel Computing Toolbox Instructions Download the folder containing the main code (ExoCT_code.m), the parameter setting with two example settings (User_setting_ex1.m and User_setting_ex2.m), the folder ‘/Functions’ containing the supporting functions (FDK.p, Filtering.p, Geometry_initialization.p, Stack_saving.p), and two sinograms contained in the folder ‘/Sinograms’ to be used with the user setting examples (PP1_sino.tif and PP3_sino.tif). Define parameters in User_setting_*.m, in detail: param.sinogram: filename or full path in case the folder containing the sinogram is different from “Sinogram” folder provided param.horizontal: “true” if the angle of projections varies along the horizontal axis, “false” if along the vertical axis param.log: “true” if the sinogram pixel values are expressed as logarithm, “false” otherwise param.gpu: “1” to enable the use of GPU, “0” to disable it param.px_size: pixel size in millimeters param.DSD: source-detector distance in millimeters param.DSO: source-object distance in millimeters param.tot_angle: total scanning angle param.dir: “-1” if the gantry rotates counterclockwise, “1” if the gantry rotates clockwise param.PP: number of projections per oscillation period param.amplitude: full amplitude oscillation in millimeters param.vx: voxel size along x axis in millimeters param.vy: voxel size along y axis in millimeters param.vz: voxel size along z axis in millimeters param.filter: the available filters are “ram-lak”, “shepp-logan”, “cosine”, “hamming”, “hann” param.save: “true” to save the reconstructed volume, “false” otherwise. Run ExoCT_code.m The output volume will be saved in the dedicated subdirectory Reconstructed_volume. Each of the reconstructed axial slice will be saved as a separate 32-bit ASCII file

    iPSC Gene Editing

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    Although both the iPSC and CRISPR technologies have advanced considerably recently, handling of iPSCs throughout the genome engineering process requires a special skill set for accurate genetic modification while maintaining the health and pluripotency of iPSC lines. This is where Creative Bioarray's expertise lies

    Note Illustrative della Carta geologica d'Italia alla scala 1:50.000 F. 180 Salsomaggiore Terme, Servizio Geologico d'Italia - ISPRA

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    Note illustrative redatte per il Foglio geologico n. 180 Salsomaggiore Terme della Carta Geologica d'Italia alla scala 1:50.000. 112 pp

    Note Illustrative della Carta geologica d'Italia alla scala 1:50.000, F. 077 Clusone, Servizio Geologico d'Italia - ISPRA

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    Note illustrative redatte per il Foglio geologico n. 077 Clusone della Carta Geologica d'Italia alla scala 1:50.000. 232 pp

    Oncolytic Virus Service

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    Oncolytic viruses (OVs) are a class of viruses that can selectively replicate in and lyse cancer cells, and subsequent spread with a tumor while not causing damage to normal cells. They have tremendous therapeutic potential to target and kill cancerous cell. Oncolytic virotherapy is an innovative treatment modality which uses replication competent viruses to destroy malignant cancers

    Accessibilità delle Web APP della DSI

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    Rendere un’applicazione web accessibile, oltre ad essere un dovere sociale, permette ad ogni utente di poter usufruire delle sue funzionalità in un modo più profittevole. Gli aspetti caratterizzanti l’accessibilità si dividono in due categorie principali: visibili e invisibili. I primi sono degli aspetti di cui l’utente ha un’esperienza diretta e sono ad esempio i colori utilizzati e il modo in cui sono realizzati gli elementi interattivi della pagina. I secondi, invece, corrispondono al modo in cui le pagine web sono codificate e possono essere analizzate da un lettore automatico. In questa trattazione saranno discusse entrambe le tipologie di aspetti e il focus sarà puntato sulla loro gestione nell’ambito dello sviluppo interno alla DSI, che ha tra i propri obiettivi la realizzazione di applicativi web a supporto delle attività amministrative dell’INFN

    1876-1881: Domenico Lovisato and the geology of Calabria (southern Italy)

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    Celebrating the centennial of Domenico Lovisato’s death (1842-1916), this paper highlights the role played by this eminent Italian geologist as a pioneer for the geological knowledge of Calabria region (Southern Italy), a geologically complex area which became the subject of a long-lasting and still continuing debate. Lovisato spent only few years in Calabria (1876-1878) teaching as high school professor of mathematics; this period marked a turning point for his scientific growth representing a switch for his career from avocational to full-time geologist. This experience granted him the involvement in the academic career, with the enrollment in the University of Sassari and Cagliari as Professor of Mineralogy and Geology (from 1878 until his death, in 1916). Lovisato must be acknowledged as the author of the first 1:50,000 geological map of the Calabria region. As such, he should be mentioned for his ethic approach towards environment, anticipating the catastrophic effect of natural phenomena and the modern concepts of geoethic

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