MOTIVATIONAL MECHANISMS OF ROSACEA TIDES: Part I

The subject of the study – rosacea tides. The aim of the study was to find out the triggering role of sexual motivations in the development of rosacea tides. These data indicate the role of sexual motivation as a vital need and in case of failure of a number of necessary mechanisms for its implementation there are disorders in the leading centers of regulation of homeostasis, the earliest - in the hemodynamic center, which becomes one of the triggers of labile vascular response. in the centers of the brain and in the microcirculatory tract of the skin.Keywords: rosacea tides, sexual motivation, vascular reactions

THE EMOTIONAL COMPONENTS OF THE PATHOGENESIS AND CLINIC OF ROSACEA: Part I

The subject of the study – rosacea. The purpose of the work is to provide modern data on the importance of the emotional component in the development of clinical manifestations of rosacea. These data emphasize the emotional response as a type of behavioral activity that occurs in the initial stages of this dermatosis in the motivational centers of the hypothalamus, and then - spreads generalized with the involvement of the centers of the cerebral cortex, and to the wrong pathophysiological circle cosmetic skin defect in this disease (especially in women), up to the development of manifestations of emotional stress.Keywords: rosacea, emotional centers, stress

THE CLINICAL SIGNIFICANCE OF THE KINETICS OF CELL POPULATIONS OF THE POLYSEBATION COMPLEX IN ROSACEA

The subject of the study – rosacea. The purpose of the work is the analysis of data on the clinical value of the kinetics of cells of the pilosebation complex of the skin of the face with rosacea. Own data of examination of two groups of women with rosacea patients (younger and older) are presented, as well as an analysis of modern literature, a comparison of which allows us to conclude that there are different reasons for the pustulation of rashes in the pilosebial region in different age categories of patients and the value of the kinetics of various cell populations of this complex in the development of the complicated course of the disease.Keywords: pyogenization of rosacea, pilosebation complex of the facial skin of women

ROSACEOSES AND DEMODICOSIS – COMBINED (CLINICALLY ASSOCIATED) DERMATOSES?

The subject of the study – rosacea and demodicosis. The purpose of the work is to analyze the effect of the clinical association of demodicosis and rosacea on the mutual course of these dermatoses. Materials of the analysis are given, which testifies to the disputability of assigning Demodex ticks to the etiological causes of rosacea. At the same time, in cases of their increased activity as a result of various reasons that are important for the pathogenesis of rosacea, the course of this dermatosis is complicated.Keywords: rosacea, demodicosis, clinical associations

PROBLEMATIC ASPECTS OF VEGETATIVE-VASCULAR REACTIONS IN ROSACEA TIDES: Part I

The subject of the study – rosacea tides. The purpose of the work – based on the analysis of current data to provide information about the importance of regulatory effects of the autonomic nervous system on the occurrence of hot flashes in rosacea. The data that indicate the importance of dysregulatory mechanisms at different levels of the autonomic nervous system in the development of rosacea, due to a complex of changes in hemodynamics, thermoregulation, functional status of skin structures and genitals in women.Keywords: rosacea-tides, autonomic nervous system, dysregulation of centers

STEROID HORMONE DYSREGULATORY OF ROSACEA: Part I

The subject of the study – rosacea. The aim of the work is to clarify the ways of influence of dysregulatory steroid hormonal mechanisms on the stages of rosacea development. The data that indicate a certain stage of inclusion of different ways of responding to physiological or pathological hormonal changes of steroid sex and non-sex ovarian hormones in relation to: mechanisms of their production rate, discrete secretion, cascade involvement of neurosecretes of protein and peptide nature (neurotransmitters and, target organs, which affects the clinical manifestations of different stages of dermatosis.Keywords: rosacea, steroid hormones (sexual and asexual), neurotransmitters

ROLE IN THE DEVELOPMENT OF ROSACEA SPECIAL FEMALE GENITAL CENTER: Part I

The subject of the study – rosacea. The aim of the work is to determine the possibility of considering the presence of a special female sexual center as a regulator of initial and subsequent pathophysiological changes in rosacea. The data show the relationship between regulatory molecular compounds of the hypothalamus (liberins, statins, releasing factors), pituitary gland (tropical hormones), ovaries (steroid sex hormones and non-steroidal compounds), which in the case of disorders of any of the These levels of the hypothalamic-pituitary-gonadal axis involve the molecular functional systems of other centers of the nervous and endocrine systems to overcome them. Given the clinical data on the close relationship of manifestations in women with sexual hormonal disorders, there are grounds for objectifying the presence of a functional regulatory sexual center in them.Keywords: rosacea, centers of the nervous and endocrine systems, dyshormonal sexual disorders

«LIFE QUALITY» INDICATORS IN PATIENTS WITH CHRONIC DERMATOSIS

The subject of the study – the analysis of «life quality» indicators in patients with chronic dermatosis. The purpose of a work is to compare «life quality» indicators in patients with rosacea and psoriasis with complicated and uncomplicated forms of the disease. The research is conducting with the WHOOOL-BREF Quiz – an analysis of four basic spheres, characterizing different aspects of life quality indicators of patients with rosacea and psoriasis testifies to reliable differences of the majority of scores in examined patients, comparing with average scores in «healthy people»; more pronounced differences were mentioned in complicated forms of these and others dermatosis.Keywords : rosacea, psoriasis, demodecosis, arthropathia, life quality.  Предмет исследования – анализ показателей качества жизни у больных хроническими дерматозами. Цель работы – сравнить показатели качества жизни больных розацеа и псориазом с осложненными и не осложненными формами течения заболевания. Проведение с помощью опросника ВОЗ (WHOOOL-BREF) – анализа 4 основных сфер, характеризующих различные аспекты качества жизни больных розацеа и псориазом свидетельствует о достоверных отличиях по большинству изученных показателей у обследованных больных по сравнению со среднестатистическими коэффициентами у «здоровых лиц»; более выраженные отличия наблюдались при осложненных формах этих и других дерматозов.Ключевые слова: розацеа, псориаз, демодекоз, артропатия, качество жизни

WHAT DID THE OLD PHOTOS SAY

The personalization of two photographic documents representing an obvious historical interest was held. The brief biological information about students of Microbiological courses at the Pasteur Institute depicted in the photo is presented. The facts of their involvement in the events reflected in the photos are revealed. Keywords: biography, history of national and world science, dermatology, syphilidology, Microbiological courses, Pasteur Institute, World Congress, Paris, Vienna, Odessa.Проведена персонализация фигурантов нескольких фотодокументов, представляющих очевидный исторический интерес. Представлены краткие биографические сведения о слушателях Микробиологических курсов в Институте Пастера, изображенных на фото. Выяснены обстоятельства их участия в событиях, отраженных на фотографиях. Ключевые слова: биография, история отечественной и мировой науки, дерматология, сифилидология, Микробиологические курсы, Институт Пастера, мировой конгресс, Париж, Вена, Одесса.

INTEGRATED TREATMENT OF ACNE PATIENTS WITH PEPTIDE MODULATIVE AND PHYTOANTIBACTERIAL THERAPY

The subject of the study – acne. The purpose of a work – an estimation of effectivity of the complex treatment in acne patients with Dalargin and Sangviritrin. The use of peptide modulative (Dalargin ) and phytoantibacterial (Sangviritrin) therapy allows to achieve a regress of rash in shorter terms, procures the prophylaxis of complications of the disease, and provides good clinical results in nearest and further periods of patients’ observation.Keywords: acne, laboratory diagnostics, peptide modulative (Dalargin) and phytoantibacterial (Sangviritrin) therapy. Предмет дослідження – вугрова хвороба. Мета – оцінка ефективності комплексного лікування хворих на вугрову хворобу (акне) із призначенням Даларгіну та Сангвірітрину. Використання пептидомодулюючої (Даларгін) та фітоантимікробної (Сангвірітрин) терапії дозволяє в більш коротші терміни досягти регресу висипки на шкірі, забезпечує профілактику ускладнень захворювання та добрі клінічні результати в найближчому та віддаленому періодах спостереження за хворими.Ключові слова: вугрова хвороба (акне), лабораторна діагностика, пептидомодулююча (Даларгін) та фітоантимікробна (Сангвірітрин) терапія