Leaders of Welcoming and Affirming Churches in North Carolina Discuss their Roles in HIV/AIDS Awareness and Prevention

Some church leaders work to increase HIV testing and spread messages to reduce stigma. This study focuses on how leaders of North Carolina churches considered welcoming and affirming by the LGBTQ+ community discuss and disseminate information about HIV/AIDS to church members and communities. Semi-structured interviews were conducted with six leaders of different denominations between April and May 2023. A thematic analysis of the transcribed interviews found three main approaches: 1) HIV is not addressed directly, but we are here; 2) provide access to educational resources; and 3) fight stigma. Results confirm welcoming/affirming churches could play a significant role in, not only educating their communities about HIV, but also reducing the stigma associated with the disease

Comparative Analysis of Phytocompound Variations in Leaves, Bark and Roots of Allspice (Pimenta Dioica) Collections in Tanzania

Allspice, scientifically known as Pimenta dioica, holds potential as a natural source of beneficial compounds that have been historically used to address various human health concerns. The aim of this research was to explore differences in the compounds found in parts of Allspice (i.e., the leaves, bark, and roots). Petroleum ether, dichloromethane, and methanol were used to extract the substances from each part; the resulting crude extracts were then analyzed using gas chromatography mass spectrometry. To interpret the obtained data, the National Institute of Standards and Technology database was referred to for a spectra analysis. The findings indicated that the leaves contained 81 phytocompounds, bark had 18 types, and roots exhibited 12 varieties. Prominent phytocompounds found in the leaves were eugenol in 72.24% – 73.91% of the total compounds detected. Bark was primarily composed of 1,4-Methanoazulene, decahydro-4,8,8-trimethyl-9-methylene-, [1S-(1. alpha.,3a. beta.,4. alpha.,8a. beta.)] in 74.35% – 84.24%; while roots contained γ-sitosterol at an 86.08% concentration level. In terms of solvent performance, methanol exhibited high efficiency on leaves, while dichloromethane demonstrated optimal results on bark and roots. The findings confirm significant variations in phytocompound composition in different parts of Allspice and underscores the importance of considering specific types of phytocompounds, as well as extraction techniques to achieve valuable outcomes

Can Stem Cell Therapy be an Effective Therapeutic Option for Complex and Neurological Conditions?

This article explores the feasibility and potential benefits of stem cell therapy as a promising therapeutic intervention for individuals facing severe behavioral and cognitive impairments, targeting underlying neurological mechanisms to offer potential symptom improvement and function restoration, thereby enhancing the quality of life for patients and potentially alleviating stress and burnout among caregivers. The aims of the study include investigating the efficacy of stem cell therapy in addressing these impairments and evaluating its potential to alleviate caregiver burden. Through a comprehensive review of existing literature, clinical trials, and studies, this research synthesizes the mechanisms of stem cell therapy, potential applications, clinical trial outcomes, caregiver experiences, and economic implications. The methods employed involve analyzing diverse data sources to provide a holistic understanding of the possibilities and challenges associated with stem cell therapy. Key outcomes of the study include highlighting promising results from clinical trials targeting conditions such as autism spectrum disorder, Parkinson's disease, and Crohn's disease, which underscore the transformative potential of stem cell therapy in patient care. Additionally, economic implications suggest potential reductions in healthcare costs and alleviation of financial strain on individuals, families, and healthcare providers. Stem cell therapy represents a paradigm shift in healthcare, promising to redefine treatment approaches and alleviate broader societal burdens associated with complex neurological conditions. The relevance of the study lies in emphasizing the need for continued research, ethical considerations, and multidisciplinary collaboration to ensure the safe and effective integration of stem cell therapy into clinical practice, ultimately offering new hope and improved care for patients, caregivers, and healthcare systems worldwide

Are Technologies Useful and Easy to Use: Results of A Cross-Sectional Survey

Tools and technologies have strengths and weaknesses and can either reduce or increase complexity and make work easier or harder. This article aims to report the results of a survey that assessed the usefulness and ease of use of tools and technologies, and perceptions of participants about tools and technologies as a factor in complexity and project failure. A cross-sectional survey of 114 project managers, researchers, and decision-makers was conducted to assess if tools and technologies that participants use in their work are useful and easy to use by asking two questions based on a validated tool of user acceptance of technologies. Additionally, two questions asked participants which tools and technologies were most helpful in their work – one was an open question, and the other provided pre-selected choices of tools and technologies. Few participants chose tools and technologies as a factor that contributes to complexity and project failure, and most participants rated tools and technologies as useful and easy to use. However, the tools and technologies that were chosen by most as helpful for work, tend to be older and simpler and include tools such as checklists. In conclusion, even though tools and technologies are advancing rapidly, most participants in the current survey chose older tools and technologies as helpful in their work. The relevance of these findings is that there appears to be barriers to the adoption of newer technologies such as artificial intelligence and algorithms. The barriers to the adoption of new tools and technologies should be explored further

The Impact of the 2021 Fire in the Municipality of Ancient Olympia in Greece on the Mental Health of Residents: The Occurrence of Post-Traumatic Stress and Depression in Beneficiaries of Social Services

A natural disaster is the probability of a potentially catastrophic event occurring over a period of time in a specific geographical area. The aim of this research was to investigate whether the catastrophic fire of 2021 affected the mental health, in terms of post-traumatic stress and depression, of the social care services beneficiaries in the Municipality of Ancient Olympia in Greece. A questionnaire was used which, apart from demographic questions, contained two main tools: a) the PCL Scale (a tool for assessing post-traumatic stress), b) the Geriatric Depression Scale. The individuals with post-traumatic stress in the sample are in the range of moderate to high PTSD symptomatology. The majority of the participants are in the range of moderate PTSD symptomatology, but there is also a significant percentage who are in the range of high PTSD symptomatology. In terms of geriatric depression, the individuals in the sample are close to the mean. This article was written to serve as reference for the PTSD that can be directly caused by natural disasters

Intersectionality in Educational Psychology and Curriculum Studies: A Critical Review

The review article draws on key literature on intersectionality: theory, methodology, and empirical applications in Educational Psychology and Curriculum Studies. The review points out the urgent need to account for diverse learners’ intersectional identities (racial/ethnic backgrounds, gender, linguistic ability, citizenship status, and other social identity markers) and embrace a social-justice-oriented praxis in education. We argue that integrating the intersectionality framework with existing learning theories, methods (quantitative, qualitative, and mixed), and pedagogies is possible and necessary. Based on the critical review, we propose four recommendations for researchers and practitioners in Educational Psychology and Curriculum Studies: (a) staying faithful to the activism and liberatory commitment of intersectionality, (b) adopting appropriate method(s) and methodology with sound epistemological and axiological orientations, (c) reconceptualizing extant learning theories, which entails the re-thinking and validation of some education and psychological constructs, and (d) encouraging teaching and research on intersectionality and/or from an intersectional lens. The review article can serve as a guideline to incorporate intersectionality as theory and analytical framework. It is only through these practices that center intersectionality that we, as researchers and practitioners, become capable of creating a more equitable and inclusive learning environment from K-12 to Higher Education

The Value of Qualitative Methods in Cross Cultural Education: A Case Study from a First Person Perspective

This paper presents a first-person account of using qualitative research methods to address medical residency education. The results of this project have been published. However, the study's process and its educational impact on the participants have not been well-described. The purpose of this article is to describe the background and conduct of the study itself. A family medicine residency program, the setting for this project, had recently begun accepting international medical graduates (IMGs) who had lived and received medical school education outside of the United States. The author, a faculty member in the residency and a clinical psychologist, and the physician faculty observed residents as they saw patients in the family medicine residency clinic. Concern was expressed about some of the IMG resident physicians’ knowledge base and their ability to develop rapport with patients. In providing instruction in behavioral science, the author and a psychologist colleague noted that some of the IMG residents were confused by aspects of U.S. family life and the educational system. The relationship with clinical instructors and expectations of faculty also differed from the pedagogical norms in U.S. medical education. As a result, a qualitative interview project was undertaken to understand better how these IMG residents were experiencing and interpreting faculty-learner and resident physician-patient interactions. The results were beneficial in multiple ways. First, recognizing that faculty members were interested in their experiences helped develop rapport and trust between the faculty and residents. Providing the project results to the residents helped open discussion about cultural differences in medical education and patient care. For educators who may have difficulty understanding the perspective that learners bring to their education, the process described could be of potential benefit

Predictors of Households’ Adoption of Gas Cooking Stove in Some Rural Communities of Abia and Ebonyi States, Southeast Nigeria

This paper aims at the factors that predict household’s adoption of gas cooking stoves in selected rural communities of Southeast Nigeria. Leaning on theories of Knowledge gap, Groupthink, Technological determinism and Innovation Diffusion, it explores the theme of adoption as a selective process while interrogating the idea of an energy ladder. The paper probes the factors that accentuate poor energy choices in the face of availability of the better domestic energy source, gas. Based on data from 600 respondents, 300 from each of the southeastern Nigeria states of Abia and Ebonyi, an ordinal regression in the form of a Generalized Linear Model was used to predict the proportional odds of the dependent ordinal variables. Parameter estimates of the regression model predicting ordinal likelihood (odds) of using cooking gas indicate that none of the categories underage bracket were significant. The odds of households with male heads having very high usage of cooking gas stove were 1.563 (95% CI, .882 to 1.830) times more than that of households with female heads. The odds are against larger households; households with heads that are of lower education levels; households that regularly cook with fuelwood and those with lower income. The study recommends advocacy to bridge the knowledge gap and a subsidization regime that can overcome the income challenge

Differential Perspectives Between miRNA and lncRNA in Light of Biogenesis and Functions: A Review

The central dogma is suggested that deoxyribonucleic acid is translated into ribonucleic acid (RNA) and then into protein. It is considered that 2–3% of the genomic DNA in a functionally active cell, is transcribed to protein-coding RNA. The presence of noncoding transcripts has been neglected many a time as cellular DNA and transcript noises, however, increasing proof proposes that a very important part of these non-coding transcripts is functionally effective as RNA molecules. The non-coding transcripts of up to 100 bases are known as small non-coding RNA that comprises tRNA, miRNA, snoRNA, piwi-interacting RNA (pi-RNA), etc. Interestingly, rRNA features about 6.9 kb, though these are not considered long-non-coding RNAs. However, RNA molecules that are over 200 bases long (ranging between 0.8 to 10 kb) are known as long non-coding RNA (lncRNA). It does not have open reading frames (with some exceptions), 3`- untranslated regions (3’-UTRs), and these RNAs are devoid of any translation-termination regions. However, these may be capped, spliced, and polyadenylated as RNA molecules and play a major role in factor regulation, neoplastic cell invasion, chromatin granule transforming, and cell differentiation. Downregulation of lncRNA is responsible for numerous diseases in mammals. miRNAs are mature transcripts of 22 nt in length and function as antisense regulators of other RNAs. They play role in post-transcriptional factors and are involved in differentiation, proliferation, immune response, cell growth, and caspase-mediated cell death. Downregulation in miRNA expression has a necessary role in many diseases, together with cancers

Variable Conceptualisation and Measurement in Environmental Research

This paper discusses the importance of variable conceptualisation and measurement in environmental research. The paper explains how wrong application of concepts can mislead the researcher when conducting research, and the resultant effects on each stage of the environmental research process. The paper is motivated by the problems behind many research students pursuing their masters or doctoral degree programmes face, especially with change in dissertations or theses titles and methods to match the contents of their reports. In this paper, the authors demystify the challenges encountered by unskilful researchers and students when trying to make their readers have a clear understanding of their research reports (dissertations or theses). Therefore, the paper may serve as a guide in planning and conducting environmental research by university degree students and early career researchers