The Operation Management Model of Intermittent Irrigation in Cihea Irrigation Area In Cianjur Regency

The availability of water for irrigation has been decreasing and the need for other sectors has been increasing rapidly over the time. Whereas, there are also several environmental damages due to the serious exploitation of natural resources in many places. This situation causes the irrigation system has to be managed efficiently and effectively. In irrigation modernization, the implementation of intermittent irrigation is the right choice, because it is a water-saving irrigation technology. The model operation of intermittent irrigation operation that is built is a calculation model to determine the interval of irrigation water provision and the amount of irrigation water, which begins with the planning of the cropping pattern. The irrigation operation management model with intervals of providing irrigation water for 3 days developed in the Cihea Irrigation Area, Cianjur Regency has an influence on irrigation performance. The paddy planting season in Cihea, Cianjur Regency with intermittent irrigation operation, was able to achieve irrigation water productivity values> 0.8-1.0 kg / m3 (advanced stage in modern irrigation management

Hematologic toxicities of chemotherapy in lung cancer patients: A retrospective study in Dr. M. Djamil Hospital Padang, Indonesia

The use of chemotherapeutic agents in the management of cancer is often followed by a range of toxicities to various organ systems. A retrospective study on the hematologic toxicities of chemotherapy in lung cancer patients has been carried out. The study was conducted by a cross-sectional method from medical records of four-year data in 2010–2014 at Dr. M. Djamil Hospital Padang, West Sumatra, Indonesia. Data from medical records of patients diagnosed with lung cancer and underwent chemotherapy, not suffering from primary hematologic diseases, and with normal kidney and liver function prior to chemotherapy were studied. A number of 22 medical records of lung cancer patients which met the criteria with a total of 40 chemotherapy cycles were observed. The study revealed that a combination of carboplatin-paclitaxel was the most common chemotherapy used for the patients (72.7%). The hematologic toxicities comprised anemia, leukopenia, and thrombocytopenia with the severity ranging from grade 1–3. Carboplatin-paclitaxel was the only combination that caused these three toxicities, and the only combination to cause thrombocytopenia as well. Anemia was the major hematologic toxicity experienced by more than half of the patients. The study concludes that there is a reasonably high incidence of hematologic toxicities from chemotherapy among lung cancer patients

Pharmacodynamics effect of methylprednisolone tablets on the serum concentration of annexin A1: in vivo comparative study between generic and innovator drug

Objective: The aims of this study were to investigate the comparative pharmacodynamics effect of methylprednisolone (MP) innovator, MP branded generic, and MP generic products to the serum concentration of annexin A1 (AnxA1). Methods: It was conducted by two-way crossover design in male rabbits. AnxA1 was measured at 0, 0.5, 1, 2, 3, 5, 7, and 9 h after the administration of the drugs. The peak concentration (Cmax ), the time at which the peak concentration was achieved (Tmax ), and the area under the plasma concentration- time curve (AUC) were also determined. Results: The highest concentration and widest AUC of AnxA1 were obtained in MP innovator drug. MP innovator and branded generic reaches the peak time (Tmax ) at the third 3rd h, while the MP generic reaches the peak time at the 5th h. The results showed that there was no significant difference in the serum concentration of AnxA1 between MP tablets after analyzed with a one-way analysis of variance. Conclusion: It could be concluded that the innovator drug of MP tablet gave the same effect on the serum concentration of AnxA1 than its generic counterparts, but an onset of action MP innovator and branded generic is faster than the generic product

Terlibat dalam kegiatan persamaan persepsi dalam rangka kegiatan kepaniteraan mahasiswa prodi gizi

ST Nomor: 1152.a/UN16.12.D/KP/201

Mengajukan proposal pengabdian kepada masyarakat berjudul: Upaya Peningkatan Kualitas Hidup dengan Penerapan Pola Hidup Sehat Pada Penderita Diabetes Mellitus dan Hipertensi dalam Klub Prolanis Kota Padang

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