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Other Lovings: An AfroAsian American Theory of Life
Introduction: Other lovings and racial ontology -- Audre Lorde and affectable flesh -- David Henry Hwang and Asian American love-being -- The Amiri Baraka of surplus love -- Jeremy Lin, G Yamazawa, Lyricks: an AfroAsian commons -- Gayl Jones and somatic wisdom -- Adrian Tomine and the love of the Asian American object -- Theodor Adorno, Eve Sedgwick, and the Kyoto School's optimism -- Conclusion: bell hooks's and Charles Yu's love-being in practice.Item embargoed for five year
How Gremlins Opened the Door for Patent Trolls at the International Trade Commission: The ITC Subverts Its Own Mission by Turning Legal Coercion Into a "Domestic Industry" and Punishing Productive American Companies
Prediction of Optimal Parameters for Wire-Arc DED Welding Using a Multilayer Perceptron Trained on Synthetic Data Generated by a Generative Adversarial Network
The global demand for 3D printing technologies has grown significantly, influencing various industries and extending into the welding sector through additive manufacturing (AM). In welding, AM involves constructing metal parts layer by layer using wire or powder feedstock. This method offers advantages such as material efficiency and design flexibility. However, bead overlapping between layers often results in defects like surface irregularities and weakened structural integrity.
This paper presents an automated approach to optimize welding parameters using a multi-layer perceptron (MLP) neural network. Traditional methods for selecting parameters such as current, voltage, and wire feed rate are time-consuming and resource-intensive. To address limited data availability, synthetic data were generated using a generative adversarial network (GAN).
By training the MLP on this expanded dataset, the system predicts parameters that improve bead quality and inter-layer bonding. This AI-driven approach reduces the need for extensive physical experimentation, minimizes material waste, and shortens development cycles.No embargoAcademic Major: Computer and Information Scienc
The Impacts of Plasma Treatment on Airborne Microorganisms for Space Environment Applications
In space environments, microorganisms such as bacteria and fungi exhibit enhanced growth parameters and resilience to antibiotics, complicating mitigation efforts. This behavior increases risks of structural damage to the spacecraft and health issues such as infections and hypersensitivities among astronauts in closed environments such as the International Space Station (ISS). To address this, a cost-effective, low-waste technology called CAFAAI (Cabin Atmosphere Filtration using Ambient Air Ionization) has been developed for continuous microbial neutralization using the generation of negative plasma discharge. CAFAAI is optimized for low- power operation with no moving parts, making it a low-maintenance option. This study evaluated CAFAAI’s effectiveness in neutralizing three microorganisms commonly found on the ISS – Aspergillus (filamentous fungi), Aureobasidium pullulans (polymorphic fungi), and Bacillus atrophaeus (bacterium). Cultures were nebulized and treated under two voltage potentials and two treatment durations, repeated three times. Microbial survival was assessed by collecting samples post-CAFAAI treatment and monitoring growth on agar plates after incubation. Results demonstrated that higher voltages and longer treatment durations enhanced microbial neutralization for all microorganisms tested. Furthermore, a tradeoff between treatment duration and voltage potential was observed; doubling the contact time decreased the colony forming units on the plates 3x more than doubling the voltage potential. CAFAAI’s ability to continuously reduce microbial loads without producing significant waste or requiring moving parts positions it as a promising addition to spacecraft systems. This technology offers a sustainable solution for maintaining healthier and safer environments for astronauts during long-duration missions.A one-year embargo was granted for this item.Academic Major: Aerospace Engineerin
Canonical mRNA cap binding proteins have distinct roles in regeneration from the fish specific ortholog eif4e1c
Zebrafish are valuable models for cardiac regeneration due to their remarkable ability to regenerate heart tissue. Our research focuses on the eIF4E family of translation initiation factors, which are suspected to play a role in this process. While canonical eIF4E is found in all terrestrial vertebrates and is essential for cell viability, zebrafish also contain an additional ortholog that is unique to aquatic vertebrates, called eif4e1c. Previously, we showed that deletion of eif4e1c impaired growth, survival, and heart regeneration. It is unclear whether these phenotypes result from the reduced total level of cap-binding proteins-or if eif4e1c has specialized functions. To investigate further, we used CRISPR to make zebrafish deletion mutants for canonical eif4ea and eif4eb. Concurrent deletion of eif4e1c and eif4ea resulted in a further mortality and size deficits when compared to the solo eif4e1c mutants. Compound mutants of eif4e1c and eif4eb found similar growth defects, but no exacerbation of mortality. The eIF4E family of translation initiation factors are required for viability in eukaryotes from yeast to mice. Surprisingly, deletion of both eif4ea and eif4eb did not result in any obvious phenotypic changes in survival, growth, nor heart size. However, it was found that the loss of canonical eif4ea or eif4eb alone results in improved cardiomyocyte regeneration, and impaired fin regeneration. Compound mutants of a canonical and eif4e1c lose these regeneration phenotypes suggesting a “goldilocks” threshold where eif4e1c begins to compensate fully for the loss of canonical factors. This is to say, there may be a required ratio – canonical factors to eif4e1c – which allows for compensation. These results suggest eif4e1c can fully compensate for the loss of the canonical EIF4E factors, while the canonical factors only partially compensate for the loss of eif4e1c. This suggests that the fish specific eif4e1c ortholog is a bona fide translation initiation factor with additional functions that impact growth and survival.No embargoAcademic Major: Biolog
Neural Correlates of the Development of Word Laterality in the Visual Word Form Area (VWFA) During Early Childhood
Introduction: Humans have long been fascinated with how the brain is organized to support complex cognitive functions. One key finding is cortical specialization; the brain harbors many regions specialized to carry out specific cognitive functions. Many of these functional regions display lateralization, meaning they are more specialized to one hemisphere than the other. The Visual Word Form Area (VWFA) is one such region. The VWFA is an area of ventral temporal cortex (VTC) specialized for written scripts, and it develops category selectivity only after literacy. In adults, this word selectivity is dominant on the left. The experience dependent nature of the VWFA makes it a prime opportunity to investigate the development of functional laterality in the human brain, potentially revealing domain general mechanisms also related to the development of other lateralized functions. Therefore, we ask, what neural correlates relate to the development of word laterality in young children?
Methods: We tested two potential sources of this word laterality: 1) structural connectivity of the VWFA with the high-level language network in frontal and temporal cortices and 2) activation in these language regions. To do so, we scanned reading children (4-13 years) on a visual fMRI task to define word and face regions as well as a separate auditory fMRI localizer to estimate language responses and collected diffusion-weighted imaging (DWI) to examine white matter connectivity. We defined face, word, and (spoken) language regions for each individual child and independent runs were used to extract activation to each condition to calculate selectivity and laterality; probabilistic tractography was used to quantify white matter connections between these regions.
Results: Word selectivity was significantly left lateralized in our sample of young children. The magnitude of word laterality did not correlate with age, indicating variability in word laterality may be driven by other factors. Word laterality was positively and significantly related to laterality of the VWFA’s connectivity with frontal language regions. Additionally, word laterality correlated with auditory language selectivity in both frontal and temporal language regions. Laterality of language selectivity in these same regions was also positively and significantly related to word laterality.
Conclusion: Our findings suggest that both connectivity to related regions and activation patterns in those connected regions may play a role in the development of functional laterality. Additionally, our investigations shed further light on the development of the neural circuitry that underlies reading behavior.OSU Center for Cognitive and Behavioral Brain Imaging (CCBBI), 2024 Gibson Research AwardThe College of Arts & Sciences at OSU (Dr. Saygin)The Chronic Brain Injury program at OSU (Dr. Saygin)R01 HD110401-01 (Dr. Saygin)A one-year embargo was granted for this item.Academic Major: Neuroscienc
Council on Academic Affairs: Minutes (March 19, 2025)
Minutes from the Council on Academic Affairs' meeting on March 19, 2025