Codex Cumanicus’un Söz Varlığı ile Kumuk Türkçesinin Söz Varlığının Ses ve Anlam Farklılığı Görülmeyen Kelimeler Bakımından Karşılaştırılması

&nbsp;Ses ve anlam değişmeleri lehçeler arasında görülebilen, bir dilin lehçelerindeki ayırt edici özelliklerden birisidir. Ses değişmeleri kelime başlarında, kelime ortalarında ve kelime sonlarında görülebilir. Lehçeler arasındaki bu ses değişmelerinin en önemli sebeplerinden birisi de zamanla lehçeler arası farklılıkların oluşmasıdır. Öte yandan Eski Türkçeden gelen, yazılışları ve anlamları aynı olan kelimeler yaşanılan coğrafyaya ve zamana göre farklı anlamlara sahip olmuştur. Kıpçak Türkçesinin önemli dil yadigârlarından olan Codex Cumanicus ile günümüzde Kafkasya bölgesinde konuşulan Kumuk Türkçesinin ses ve anlam özellikleri bakımından karşılaştırmalı olarak daha önce hiç ele alınmamış olması bizi böyle bir konuda çalışma yapmaya yönlendirmiştir. Çalışmada Codex Cumanicus ile Kumuk Türkçesinin ses ve anlam bakımından farklılık göstermeyen sözcüklerinin karşılaştırması yapılacaktır. Çalışmada Kıpçak Dönemi eseri olan Codex Cumanicus ve Kumuk Türklerinin kelimelerini içeren Kumuk Türkçesi Sözlüğü ön planda olacak, ses ve anlam farklılaşması görülmeyen kelimeler araştırılacaktır.&nbsp;&nbsp;</p

Diabetic corneal neuropathy and its relation to the severity of retinopathy in patients with type 2 diabetes mellitus: an in vivo confocal microscopy study

Purpose: To investigate corneal neuropathy and corneal nerve alterations in type 2 diabetes mellitus (DM) patients with different diabetic retinopathy (DR) status. Methods: A total of 87 eyes of 87 patients with DM and 28 eyes of 28 healthy control subjects were included in the study. DM patients were further classified into 3 groups: patients without DR (NDR), patients with non-proliferative DR (NPDR), and patients with proliferative DR (PDR). PDR patients were classified into 2 groups regarding having undergone retinal argon laser photocoagulation treatment (ALP). Ocular surface disease index score (OSDI), average tear break-up time (A-BUT), corneal sensitivity and cornea nerve fiber length (CNFL), cornea nerve fiber density (CNFD), and cornea nerve branch density (CNBD) of the cornea subbasal nerve plexus (SBNP) were measured using in vivo confocal microscopy (IVCM). Results: OSDI scores increased and A-BUT decreased in DM patients compared to the control group, but no significant difference was found between DM patient groups. Corneal sensitivity decreased in DM patients who developed DR, compared to both the controls and the NDR group. CNFD and CNFL decreased in NPDR and PDR patients compared to controls. CNFD and CNBD decreased in patients who had developed PDR, compared to all three groups. All IVCM parameters decreased with DR progression. Conclusion: IVCM can detect early structural corneal nerve changes in diabetic patients. The presence of DM affects ocular surface parameters, especially in long-term DM patients. Corneal sensitivity loss is increased with the presence of DR. All IVCM parameters decrease with DR development and its progression

BSN: Photometric Light Curve Analysis of Two Contact Binary Systems LS Del and V997 Cyg

The light curve analyses and orbital period variations for two contact binary stars, LS Del and V997 Cyg, are presented in this work which was conducted in the frame of the Binary Systems of South and North project. Ground-based photometric observations were performed at two observatories in France. We used the Transiting Exoplanet Survey Satellite (TESS) data for extracting times of minima and light curve analysis of the target systems. The O − C diagram for both systems displays a parabolic trend. LS Del and V997 Cyg’s orbital periods are increasing at rates of dP/dt = 7.20 × 10−08 days yr−1 and dP/dt = 2.54 × 10−08 days yr−1, respectively. Therefore, it can be concluded that mass is being transferred from the less massive star to the more massive component with a rate of dM/dt = -1.96 × 10−7 M ⊙ yr−1 for the LS Del system, and dM/dt =-3.83 × 10−7 M ⊙ yr−1 for V997 Cyg. The parameters of a third possible object in the system are also considered. The PHysics Of Eclipsing BinariEs Python code was used to analyze the light curves. The light curve solutions needed a cold starspot due to the asymmetry in the LS Del system’s light curve maxima. The mass ratio, fill-out factor, and star temperature all indicate that both systems are contact binary types in this investigation. Two methods were applied to estimate the absolute parameters of the systems: one method relied on the parallax of Gaia DR3, and the other used a P − M relationship. The positions of the systems are also depicted on the M − L, M − R, q − L ratio, and log M tot − logJ 0 diagrams. We recommend that further observations and investigations be done on the existence of a fourth body in this system

Comparison of SARC-F and Ishii score in screening for sarcopenia in older adults with type 2 diabetes mellitus: which screening tool should we use?

BackgroundSarcopenia is common in older adults, and type 2 diabetes mellitus (DM), highly prevalent in older adults, is a risk factor for sarcopenia. Early detection of sarcopenia is vital for the implementation of preventive and therapeutic measures.ObjectiveWe aimed to compare the SARC-F questionnaire and Ishii score screening methods for sarcopenia in patients with type 2 DM.MethodsThis cross-sectional study was conducted on 462 older adults with diabetes aged >= 60. Muscle mass and strength were assessed using the BIA device and handgrip dynamometer. Sarcopenia was defined in line with the European Sarcopenia Working Group 2 (EWGSOP2). The SARC-F questionnaire and Ishii score in screening for sarcopenia were compared.ResultsThe median age was 72 (67-76) for males and 68 (65-74) for females. The prevalence of sarcopenia based on the Ishii score, SARC-F, and EWGSOP2 was 28.4%, 40.9%, and 61.9%, respectively. The sensitivities of Ishii score and SARC-F in screening for sarcopenia were 84% and 47%, respectively. The Ishii score and SARCF specificities were 67% and 69%, respectively. PPV and NPV for the Ishii score were 79% and 45%, respectively. The PPV and NPV for the SARC-F were 71% and 55%, respectively. The AUC values of the Ishii score and SARC-F were 0.790 and 0.598, respectively.ConclusionThe Ishii score can be used in daily practice to screen for sarcopenia in older adults with type 2 DM

Prognostic and diagnostic utility of pancreatic stone protein in pediatric sepsis and mortality

Background/aim: Early detection and prognosis of sepsis in critically ill children is crucial. The aim of this research was to investigate the prognostic ability of pancreatic stone protein (PSP) in validating sepsis and predicting mortality in a prospective observational study. Materials and methods: In a single-center study, pediatric intensive care unit patients were divided into cohorts of confirmed and suspected sepsis, as well as survivors and nonsurvivors. Patients with positive blood culture growth were considered to have confirmed between PSP and alternative inflammatory markers and mortality indices were then analyzed. The diagnostic and prognostic applicability of PSP for sepsis confirmation and mortality prediction was assessed using receiver operating characteristic curve analysis. Results: PSP levels were significantly elevated in patients with confirmed sepsis and within the nonsurvivor segment. In confirming sepsis and predicting mortality, PSP outperformed CRP and PCT in terms of sensitivity. It had sensitivity of 95% in diagnosing sepsis at a cut-off level of 50 ng/L, with an area under the curve (AUC) of 0.67 (95% CI: 0.52-0.81), and sensitivity of 92% in predicting mortality, with an AUC of 0.71 (95% CI: 0.56-0.83). In addition, PSP showed significant correlations with CRP, PCT, and mortality scores. Conclusion: PSP is emerging as a highly sensitive marker for confirming sepsis and predicting mortality in critically ill pediatric patients. Incorporating the PSP biomarker into routine clinical practice could potentially improve the management of pediatric sepsis

Crystal structure and Hirshfeld surface analysis of 1-[6-bromo-2-(4-fluorophenyl)-1,2,3,4-tetrahydroquinolin-4-yl]pyrrolidin-2-one

In the title compound, C19H18BrFN2O, the pyrrolidine ring adopts an envelope conformation. In the crystal, molecules are linked by intermolecular N - H...O, C - H...O, C - H...F and C - H...Br hydrogen bonds, forming a three-dimensional network. In addition, C - H...π interactions connect molecules into ribbons along the b-axis direction, consolidating the molecular packing. The intermolecular interactions in the crystal structure were quantified and analysed using Hirshfeld surface analysis