Measuring woman's perception of support and control during childbirth: psychometric proprieties of the SCIB scale in an Italian sample

ObjectiveThis study aims to develop an Italian version of the Support and Control in Birth (SCIB) and to test its reliability and validity.MethodsThe sample included 414 post-partum women, who were recruited 24/48 h after giving birth. A study-specific online questionnaire was designed to collect sociodemographic information and administer the translated Italian version of the SCIB. The construct validity of the Italian SCIB was first analyzed using Confirmatory Factor Analysis (CFA). Based on metrics showing a poor fit, Exploratory Factor Analysis (EFA) was then executed. The reliability of the instrument was verified through Cronbach’s alpha for each subscale and the total scale and test-retest correlation coefficient.ResultsCFA was performed to test the original three-factor theoretical model; however, the CFA solution showed a poor fit. Specifically, χ2 = 2100, df= 492, p ConclusionFindings enhance knowledge about childbirth by cross-culturally adapting an instrument to assess perceptions of control and support, fundamental factors in birth experience. SCIB could help health professionals to monitor women's childbirth experiences and introduce tailored interventions.</p

Bare social meanings: The production and perception of the quantifier bare

Recent sociolinguistic research on British English has identified a relatively new feature of the quantifier system, the term bare (e.g., Cheshire et al. 2008). Although the feature has been discussed in terms of its broad sociolinguistic distribution, no work has yet explored the social meaning of bare. This chapter attempts to add to our knowledge of bare by reporting on two complementary studies investigating patterns in the production and perception of quantifier bare: an ethnographic study of an East London youth club and a matched-guise study of written social media posts.The first study comprises self-recordings and interview data from 25 young people recorded in East London from 2016-2017 (Ilbury, 2019). Distributional analyses reveal that bare is, by far, one of the most frequent quantifiers (N=64) competing only with lots of. Amongst the young people, bare commonly occurs with other features of MLE. Exploring its interactional function, we speculate that its social meaning is tied to dimensions of ‘youth’ and ‘cool’ amongst this demographic of users.To test the perception of bare amongst the population more generally, the second part of the chapter considers data of a matched-guise experiment from 100 participants from England (aged 18–61, 30M 70F). We find that bare, as opposed to lots of, indexes youth and a lack of status, particularly in relation to the labels ‘educated’, and ‘formal’. However, bare is not downrated on solidarity dimensions. In fact, bare is evaluated more positively than lots of in terms of the label ‘cool’ by middle-aged and Northern participants. Ultimately, this paper contributes to our understanding of the relationship between the production and perception of quantifiers.</p

The ATLAS experiment at the CERN Large Hadron Collider: a description of the detector configuration for Run 3

The ATLAS detector is installed in its experimental cavern at Point 1 of the CERN Large Hadron Collider. During Run 2 of the LHC, a luminosity of ℒ = 2 × 1034 cm-2 s-1 was routinely achieved at the start of fills, twice the design luminosity. For Run 3, accelerator improvements, notably luminosity levelling, allow sustained running at an instantaneous luminosity of ℒ = 2 × 1034 cm-2 s-1, with an average of up to 60 interactions per bunch crossing. The ATLAS detector has been upgraded to recover Run 1 single-lepton trigger thresholds while operating comfortably under Run 3 sustained pileup conditions. A fourth pixel layer 3.3 cm from the beam axis was added before Run 2 to improve vertex reconstruction and b-tagging performance. New Liquid Argon Calorimeter digital trigger electronics, with corresponding upgrades to the Trigger and Data Acquisition system, take advantage of a factor of 10 finer granularity to improve triggering on electrons, photons, taus, and hadronic signatures through increased pileup rejection. The inner muon endcap wheels were replaced by New Small Wheels with Micromegas and small-strip Thin Gap Chamber detectors, providing both precision tracking and Level-1 Muon trigger functionality. Trigger coverage of the inner barrel muon layer near one endcap region was augmented with modules integrating new thin-gap resistive plate chambers and smaller-diameter drift-tube chambers. Tile Calorimeter scintillation counters were added to improve electron energy resolution and background rejection. Upgrades to Minimum Bias Trigger Scintillators and Forward Detectors improve luminosity monitoring and enable total proton-proton cross section, diffractive physics, and heavy ion measurements. These upgrades are all compatible with operation in the much harsher environment anticipated after the High-Luminosity upgrade of the LHC and are the first steps towards preparing ATLAS for the High-Luminosity upgrade of the LHC. This paper describes the Run 3 configuration of the ATLAS detector.</p

Taiwan Bat Lyssavirus: In Vitro and In Vivo Assessment of the Ability of Rabies Vaccine-Derived Antibodies to Neutralise a Novel Lyssavirus

Rabies is a neglected tropical disease. The prototype virus, the rabies virus, still causes tens of thousands of human fatalities annually. Rabies is one member of the genus Lyssavirus. The burden of other lyssaviruses is unclear. The continued emergence of novel lyssaviruses means that assessment of vaccine efficacy against these viruses is critical, as standard rabies vaccines are not efficacious against all lyssaviruses. Taiwan bat lyssavirus (TWBLV) was first reported in 2018 following isolation from Japanese house bats. Since the initial detection and genetic characterisation, no attempts have been made to antigenically define this virus. Due to the inaccessibility of the wildtype isolate, the successful generation of a live recombinant virus, cSN-TWBLV, is described, where the full-length genome clone of the RABV vaccine strain, SAD-B19, was constructed with the glycoprotein of TWBLV. In vitro and in vivo characterization of cSN-TWBLV was undertaken and demonstrated evidence for cross-neutralisation of cSN-TWBLV with phylogroup I -specific sera and rabies virus standard sera. For neutralisation equivalent to 0.5 IU/mL of WHO and World Organisation of Animal Health (WOAH) sera against CVS, 0.5 IU/mL of WOAH sera and 2.5 IU/mL of WHO sera were required to neutralise cSN-TWBLV. In addition, specific sera for ARAV and EBLV-1 exhibited the highest neutralising antibody titres against cSN-TWBLV, compared to other phylogroup I-specific sera.</p

National and subnational short-term forecasting of COVID-19 in Germany and Poland during early 2021

Background: During the COVID-19 pandemic there has been a strong interest in forecasts of the short-term development of epidemiological indicators to inform decision makers. In this study we evaluate probabilistic real-time predictions of confirmed cases and deaths from COVID-19 in Germany and Poland for the period from January through April 2021. Methods: We evaluate probabilistic real-time predictions of confirmed cases and deaths from COVID-19 in Germany and Poland. These were issued by 15 different forecasting models, run by independent research teams. Moreover, we study the performance of combined ensemble forecasts. Evaluation of probabilistic forecasts is based on proper scoring rules, along with interval coverage proportions to assess calibration. The presented work is part of a pre-registered evaluation study. Results: We find that many, though not all, models outperform a simple baseline model up to four weeks ahead for the considered targets. Ensemble methods show very good relative performance. The addressed time period is characterized by rather stable non-pharmaceutical interventions in both countries, making short-term predictions more straightforward than in previous periods. However, major trend changes in reported cases, like the rebound in cases due to the rise of the B.1.1.7 (Alpha) variant in March 2021, prove challenging to predict. Conclusions: Multi-model approaches can help to improve the performance of epidemiological forecasts. However, while death numbers can be predicted with some success based on current case and hospitalization data, predictability of case numbers remains low beyond quite short time horizons. Additional data sources including sequencing and mobility data, which were not extensively used in the present study, may help to improve performance.</p

Science Communication practices and Trust in information sources amongst Nigerian scientists and journalists

Relatively few studies have explored the communication practices of researchers and journalists working in African contexts. We set out to explore the communication activities undertaken by Nigerian health researchers and journalists, their motivations and the barriers they face in communicating about health topics with lay audiences, as well as their trust in a range of sources of scientific information. The study adopted a survey methodology, recruiting 69 participants at a communications training workshop for both health researchers and journalists. We found high levels of participation in research communication amongst health researchers compared with previous work. While many barriers are similar to those faced by researchers in other contexts, our respondents highlighted that lack of support from managers is a significant hurdle, which has not been highlighted in other studies. Both journalists and researchers primarily communicate science with the aim of educating, informing, entertaining or inspiring their audiences. Regarding trust, both researchers and journalists broadly trust sources linked to science, such as academic journals. However, trust in industry, NGOs and other media was higher amongst journalists than health researchers. Least trust was invested in social media sources, with the exception of material posted on accounts linked to universities.</p

Novel avenues of tau research

INTRODUCTION: The pace of innovation has accelerated in virtually every area of tau research in just the past few years. METHODS: In February 2022, leading international tau experts convened to share selected highlights of this work during Tau 2022, the second international tau conference co-organized and co-sponsored by the Alzheimer's Association, CurePSP, and the Rainwater Charitable Foundation. RESULTS: Representing academia, industry, and the philanthropic sector, presenters joined more than 1700 registered attendees from 59 countries, spanning six continents, to share recent advances and exciting new directions in tau research. DISCUSSION: The virtual meeting provided an opportunity to foster cross-sector collaboration and partnerships as well as a forum for updating colleagues on research-advancing tools and programs that are steadily moving the field forward.</p

Production of ϒ(nS) mesons in Pb + Pb and pp collisions at 5.02 TeV

A measurement of the production of vector bottomonium states, ϒ(1S), ϒ(2S), and ϒ(3S), in Pb + Pb and pp collisions at a center-of-mass energy per nucleon pair of 5.02 TeV is presented. The data correspond to integrated luminosities of 1.38 nb-1 of Pb + Pb data collected in 2018, 0.44 nb-1 of Pb + Pb data collected in 2015, and 0.26 fb-1 of pp data collected in 2017 by the ATLAS detector at the Large Hadron Collider. The measurements are performed in the dimuon decay channel for transverse momentum pμμT </p

The most polyphagous insect herbivore? Host plant associations of the Meadow spittlebug, Philaenus spumarius (L.)

A comprehensive list of all known host plant species utilised by the Meadow Spittlebug (Philaenus spumarius (L.)) is presented, compiled from published and unpublished sources. P. spumarius feeds on 1311 host plants in 631 genera and 117 families. This appears, by a large margin, to be the greatest number of host species exploited by any herbivorous insect. The Asteraceae (222 species) and Rosaceae (110) together account for 25% of all host species. The Fabaceae (76) and Poaceae (73), are nearly tied for third and fourth place and these four families, combined with the Lamiaceae (62), Apiaceae (50), Brassicaceae (43) and Caprifoliaceae (34), comprise about half of all host species. Hosts are concentrated among herbaceous dicots but range from ferns and grasses to shrubs and trees. Philaenus spumarius is an “extreme polyphage”, which appears to have evolved from a monophage ancestor in the past 3.7 to 7.9 million years. It is also the primary European vector of the emerging plant pathogen Xylella fastidiosa. Its vast host range suggests that it has the potential to spread X. fastidiosa among multiple hosts in any environment in which both the spittlebug and bacterium are present. Fully 47.9% of all known hosts were recorded in the Xylella-inspired BRIGIT citizen science P. spumarius host survey, including 358 hosts new to the documentary record, 27.3% of the 1311 total. This is a strong demonstration of the power of organized amateur observers to contribute to scientific knowledge.</p

Whole-genome phylogeography of the intertidal snail<i> </i><i>Littorina saxatilis</i>

Understanding the factors that have shaped the current distributions and diversity of species is a central and longstanding aim of evolutionary biology. The recent inclusion of genomic data into phylogeographic studies has dramatically improved our understanding in organisms where evolutionary relationships have been challenging to infer. We used whole-genome sequences to study the phylogeography of the intertidal snail Littorina saxatilis, which has successfully colonized and diversified across a broad range of coastal environments in the Northern Hemisphere amid repeated cycles of glaciation. Building on past studies based on short DNA sequences, we used genome-wide data to provide a clearer picture of the relationships among samples spanning most of the species natural range. Our results confirm the trans-Atlantic colonization of North America from Europe, and have allowed us to identify rough locations of glacial refugia and to infer likely routes of colonization within Europe. We also investigated the signals in different datasets to account for the effects of genomic architecture and non-neutral evolution, which provides new insights about diversification of four ecotypes of L. saxatilis (the crab, wave, barnacle, and brackish ecotypes) at different spatial scales. Overall, we provide a much clearer picture of the biogeography of L. saxatilis, providing a foundation for more detailed phylogenomic and demographic studies.</p