Firm value and working capital decisions: Further evidence from an emerging market

This study investigates the effects of working capital management decisions on market values using a sample data set containing annual measurements for 317 Turkish publicly traded companies between 2010 and 2018. Cash ratio, Current ratio, Net Working Capital, and Cash Conversion Cycle are used as indicators of the liquidity policies of the sample firms. The specified dynamic model is estimated using the System GMM estimator. The findings show that firms can affect their market values by managing their liquid assets efficiently. However, this relationship weakens as cash holdings increase. In other words, a long cash conversion cycle and a large amount of net working capital are not considered negative signals by investors if accompanied by sufficient cash holdings. Hence, it can be said that cash management can help reduce the negative impact of working capital investments on firm value. This study found no evidence of the effects of the current ratio and net working capital on firm value

Histopathological and immunohistochemical evaluation of 84 uterine sarcomas according to current literature

OBJECTIVE It was aimed to reevaluate uterine sarcoma cases diagnosed in our institution within the last 20 years according to current information and to provide intra-departmental standardization in the differential diagnosis and reporting. METHODS Totally 84 uterine sarcoma cases were re-examined. Recurrence, metastasis, and prognostic data were collected from the patient files. Immunohistochemistry panel consisting of CD10, h-caldesmon, and cyclin D1 was applied to the representative tumor tissues. The relationships between the parameters studied were evaluated statistically. RESULTS Statistically significant differences were found between different histopathological types of uterine sar-comas (US) in terms of age distribution, tumor diameter, mitotic index, necrosis, depth of myometrial invasion, cervical, adnexial and/or omental involvement, lymphovascular invasion, lymph node metas-tasis, recurrence, and distant metastasis. Statistically significant correlation was determined between the prognosis of the patients and mitotic activity of their tumors and the presence of distant metastasis. The immunohistochemistry panel was found to have significant contribution to the histomorphological ex-amination in the differential diagnosis. CONCLUSION Routine use of CD10, h-caldesmon, and cyclin D1 in the histopathological evaluation of US and es-tablishing an updated standard checklist was thought to be beneficial for the differential diagnosis and reporting prognostic parameters

Oś przysadka–gonady–tarczyca i oś laktotropowa u chorych w stanie krytycznym

  Introduction: The normal circadian rhythm of hormones in critical patients becomes chaotic causing some hormones to increase and others to decrease abnormally. The goal of this study is to evaluate hormonal changes in severely ill patients and to investigate the relationship between hormonal changes and mortality and morbidity. Material and methods: We enrolled 20 patients (10 F/10 M). Blood samples were collected on day 0, day 5, and day 10. If a patient was discharged before these defined days, a sample was drawn on that day. Twenty healthy controls were included. Results: Female patients had lower LH, FSH, and fT3 and higher PRL and cortisol levels than controls on admission to the intensive care unit (ICU) (pLH = 0.021, pFSH:0.001, pfT3 = 0.021, pPRL = 0.042, pCortisol <0.001, respectively). Men had significantly low testosterone and fT3, and high PRL and cortisol levels on ICU admission (pT = 0.01, pfT3 = 0.043, pPRL = 0.005, pCortisol < 0.001, respectively). The lowest levels of gonadotropins in both genders and testosterone in men were measured on day 5. Cortisol levels decreased in the patients discharged from the ICU (p = 0.01). FSH levels increased in recovered women (pFSH = 0.043). The mortality rate was 30%. There were correlations between admission TSH and NIMV duration (p = 0.006), fT3 and APACHE II (p = 0.001), and PRL and mortality (p = 0.044). Positive correlations between E2 and APACHE II (p = 0.003) in females, and PRL and APACHE II (p = 0.022) in males were also displayed. Conclusions: Critically ill patients develop significant changes in neuroendocrine axes. Alterations in hormones correlate with the disease severity and mortality. (Endokrynol Pol 2016; 67 (3): 305–312)    Wstęp: Prawidłowy rytm dobowy wydzielania hormonów u chorych w stanie krytycznym staje się chaotyczny — wydzielanie jednych hormonów nadmiernie się zwiększa, natomiast innych maleje. Badanie przeprowadzono w celu oceny zmian stężeń hormonów u osób ciężko chorych oraz zbadanie zależności między zmianami stężeń hormonów a śmiertelnością I chorobowością. Materiał i metody: Do badania włączono 20 chorych (10 K/10 M). Próbki krwi pobierano w dniach 0, 5 i 10. Jeśli pacjent został wypisany przed tymi dniami, próbkę pobierano w dniu wypisu. Utworzono również grupę kontrolną złożoną z 20 zdrowych osób. Wyniki: U kobiet stwierdzono niższe stężenia LH, FSH i fT3 oraz wyższe stężenia PRL i kortyzolu przy przyjęciu na oddział intensywnej opieki medycznej (OIOM) niż u osób z grupy kontrolnej (odpowiednio pLH = 0,021; pFSH = 0,001; pfT3 = 0,021; pPRL = 0,042; pCortisol < 0,001). U mężczyzn w chwili przyjęcia na OIOM stężenia testosteron i fT3 były istotnie niższe, a stężenia PRL i kortyzolu wyższe niż w grupie kontrolnej (odpowiednio pT = 0,01; pfT3 = 0,043; pPRL = 0,005; pCortisol < 0,001). Najniższe stężenie gonadotropin u obu płci, a testosteron u mężczyzn zmierzono w dniu 5. Stężenia kortyzolu zmniejszyły się u chorych wypisanych z OIOM-u (p = 0,01). Stężenia FSH zwiększyły się u kobiet, których stan się poprawił (pFSH = 0,043). Odsetek zgonów wynosił 30%. Występowały korelacje między stężeniem TSH przy przyjęciu na OIOM a czasem stosowania nieinwazyjnej wentylacji mechanicznej (p = 0,006), fT3 i oceną w skali APACHE II (p = 0,001) oraz między stężeniem PRL a śmiertelnością (p = 0,044). Stwierdzono także dodatnie korelacje między stężeniem E2 a oceną w skali APACHE II (p = 0,003) u kobiet oraz między stężeniem PRL a ocean w skali APACHE II (p = 0,022) u mężczyzn. Wnioski: U chorych w stanie krytycznym występują istotne zaburzenia osi neuroendokrynnych. Zmiany stężeń hormonów korelują z ciężkością choroby I śmiertelnością. (Endokrynol Pol 2016; 67 (3): 305–312)

Methods of getting adherent of new religious movements

From the second half of the twentieth century, new religious movements such as Moonism, Hare Krishna, Scientology and etc., which especially emerge in the western world, have rapidly spread and have started to exist around the world. Moreover, extensions of these movements are also encountered in our country. There are some questions brought forward in the context of NRMs, such as how these groups gain members, which basic methods adopted while winning the fans, and how can they success to keep the supporters. In this article, it is dealt with the basic methods and practices by making use of examples of Moonism, Jehovah's Witnesses, Hare Krishna, and Mormonism, which pursue the goal of increase the members of movement.XX. yüzyılın ikinci yarısından itibarenözellikle Batı dünyasında ortaya çıkan Moonculuk, Hare Krişna, Sayentoloji vbyeni dini hareketlerin kısa sürede hızla yayılarak dünya çapında varlıkgöstermeye başladıkları ve hatta bu hareketlerin uzantılarına ülkemizde derastlandığı bir vakıadır. Bu tür oluşumların nasıl üye elde ettikleri, taraftarkazanırken hangi temel yöntemlere başvurdukları ve kazandıkları taraftarlarıellerinde tutmayı nasıl başardıkları YDH’ler bağlamında öteden beri tartışılanhususların başında gelmektedir. Bu yazıda üyelerinin sayısını artırma amacıgüden Moonculuk, Yehova’nın Şahitleri, Hare Krişna, Mormonculuk vb.hareketlerden yola çıkarak YDH’lerin taraftar kazanmada yararlandığı temelyöntem ve uygulamalar üzerinde durulmaktadır

Trakya’Da Tarla Ürünlerini (Buğday, Ayçiçeği, Kanola,Çeltik) Üreten İşletmelerin Sosyo-Ekonomik Durumu Ve Başlıca Gelişmişlik Göstergeleri İtibariyle Analizi

Kırsal alandaki toplumsal sorunların başında kuşkusuz ekonomik sorunlar gelmektedir. Daha çok tarımsal üretimin ağırlıklı olduğu bu alanlarda kişi başına gelir, bilindiği gibi ülkenin diğer alanlarına, yani kentlere oranla oldukça düşük bir düzeydedir. Öte yandan eğitim, öğretim, haberleşme, ulaşım, altyapı gibi sorunlar göz önüne alındığında kırsal alanların kalkınma sorunlarının sadece ekonomik temele dayanmadığı gerçeği ortaya çıkmaktadır. Dünyada, tüm insanların mutlu ve refah içinde yaşadığı bir ortam dileği ve stratejisi ile kırsal alanlarda yaşayanlara yönelik kalkınma arayışları hızlanmıştır. Türkiye gibi gelişmekte olan ülkelerde kırsal kalkınma çabaları ve çiftçilerin toplumsal statülerinin yükseltilmesi büyük önem taşımaktadır. Spesifik özelliklere sahip bu sektördeki kişilerin yaşam koşullarının iyileştirilmesi ve kırsal kalkınmanın sağlanabilmesi için yoksullukla mücadele politikalarının etkinliği oldukça önemlidir. Bu nedenle başlıca sosyo-ekonomik gelişmişlik göstergelerinin bölgelere ve işletme büyüklük gruplarına göre ele alınması ve irdelenmesi kaçınılmaz bir olgu olmaktadır. Bu araştırmada; Trakya bölgesindeki bitkisel üretimin % 95,4’ünü oluşturan tarla bitkileri yetiştiriciliği yapan üreticilerin başlıca gelişmişlik göstergelerinin analizi hedeflenmiştir. Bu bağlamda ayrıntılı yaşam standartları (bireylerce tüketilen mal ve hizmet miktarı) ve yaşam kaliteleri (yaşadıkları köyün altyapısı, evlerinin niteliği, gelir ve eğitim düzeyleri, mutluluk düzeyleri vb) ortaya konularak; mevcut yapı ve sorunlardan hareketle gelişmişlik düzeyinin arttırılmasına yönelik öneriler tartışılmıştır. Araştırmada, Tekirdağ, Edirne ve Kırklareli İllerinde tüm köylerdeki altyapı kalitesine ilişkin veriler elde edilerek çizelgeler haline getirilmiş ve yorumlanmıştır. İşletmelere ilişkin araştırma bulguları ise üretimin yoğunluğuna göre belirlenmiş, 6 ilçede yüz yüze görüşmeler yoluyla doldurulan toplam 144 adet anket formundan elde edilen orijinal verilerden oluşmuştur.. Çalışmada her bir ürün ve 4 farklı işletme grubu için ayrı ayrı maliyet ve kar analizleri yapılmıştır. Bu ilişkilerden hareketle Trakya Bölgesinde üretilen tarla bitkilerinden (buğday, çeltik, ayçiçeği, kanola) elde edilen gelir düzeyleri ayrı ayrı hesaplanarak, illere ve işletme büyüklük gruplarına göre kıyaslamalı olarak yorumlanmıştır. İşletmelerin elde ettikleri gelir ile yaşam kaliteleri arasındaki ilişki incelenmiştir. Araştırma sonucunda; köylerin sadece; %15,5’inde bir sağlık hizmeti, %17,1’inde PTT olanakları, %60,2’sinde şebeke suyu ve %36’sında kanalizasyon bulunduğu, %10,2’sinde su kontrolünün yapılabildiği belirlenmiştir. İşletmelerin %29’unun mutluyum diyebildiği, %43,8’inin ise bu konuda kararsız olduğu görülmektedir. Hayatından çok memnun olan çiftçiye de rastlanılmaması oldukça düşündürücüdür. Bölgesinde; karakteristik özelliklerine göre 3 farklı grup işletme belirlenmiştir.Economic problems undoubtedly comes at the beginning of problems in rural areas. The per capita income in these areas is low level compared to other areas of the country as it is known. On the other hand, problems like education, communication, transportation, infrastructure etc. shows that the development problems of rural areas are not only the economic base. In the world, strategies and wishes has been accelerated to inrease in welfare and happiness for all the people and development of the living conditions in rural areas, Raising the social status of farmers in rural areas is of great importance in developing countries such as Turkey. Specific features improving the living conditions of people in this sector and to ensure the effectiveness of poverty alleviation policies for rural development are very important. Therefore, according to the main socio-economic development, indicators should be handled by size groups. In this study; the aim is to analyse of key development indicators, detailed living standards (the amount of goods and services consumed by individuals) and quality of life (the infrastructure of the village where they live, the quality of their homes, income and education levels, happiness levels, etc.) of farmers who constitute 95.4% of the plant production of cultivated field.in the Thrace region In the study, data obtained from all villages of Tekirdag, Edirne and Kırklareli provinces about quality of infrastructure were have been tabulated and interpreted. Research findings related to enterprises's production is determined by the production density, and 144 questionnaires filled through face to face interviews in six districts. Production cost and profit analysis were realised according to four different enterprises groups each separately. This relationship of the crops produced and income derived by wheat, rice, sunflower and canola in the Thrace Region have been interpreted by provinces and farm size comperatively. And also it was investigated that the relationship between income and quality of life. Some research finding are given below; Only 15.5% of the villages have a health service, 17.1% has cominication facilities, 60.2% and 10.2% has been made for water control. 29% of enterprises say “I am happy”, it is observed that while 43.8% was hesitant on this issue. During the research; 3 different groups is determined which have different characteristics eachother

Prevalence, associated factors and outcomes of pressure injuries in adult intensive care unit patients: the DecubICUs study

Funder: European Society of Intensive Care Medicine; doi: http://dx.doi.org/10.13039/501100013347Funder: Flemish Society for Critical Care NursesAbstract: Purpose: Intensive care unit (ICU) patients are particularly susceptible to developing pressure injuries. Epidemiologic data is however unavailable. We aimed to provide an international picture of the extent of pressure injuries and factors associated with ICU-acquired pressure injuries in adult ICU patients. Methods: International 1-day point-prevalence study; follow-up for outcome assessment until hospital discharge (maximum 12 weeks). Factors associated with ICU-acquired pressure injury and hospital mortality were assessed by generalised linear mixed-effects regression analysis. Results: Data from 13,254 patients in 1117 ICUs (90 countries) revealed 6747 pressure injuries; 3997 (59.2%) were ICU-acquired. Overall prevalence was 26.6% (95% confidence interval [CI] 25.9–27.3). ICU-acquired prevalence was 16.2% (95% CI 15.6–16.8). Sacrum (37%) and heels (19.5%) were most affected. Factors independently associated with ICU-acquired pressure injuries were older age, male sex, being underweight, emergency surgery, higher Simplified Acute Physiology Score II, Braden score 3 days, comorbidities (chronic obstructive pulmonary disease, immunodeficiency), organ support (renal replacement, mechanical ventilation on ICU admission), and being in a low or lower-middle income-economy. Gradually increasing associations with mortality were identified for increasing severity of pressure injury: stage I (odds ratio [OR] 1.5; 95% CI 1.2–1.8), stage II (OR 1.6; 95% CI 1.4–1.9), and stage III or worse (OR 2.8; 95% CI 2.3–3.3). Conclusion: Pressure injuries are common in adult ICU patients. ICU-acquired pressure injuries are associated with mainly intrinsic factors and mortality. Optimal care standards, increased awareness, appropriate resource allocation, and further research into optimal prevention are pivotal to tackle this important patient safety threat

Correction to: Prevalence, associated factors and outcomes of pressure injuries in adult intensive care unit patients: the DecubICUs study

The original version of this article unfortunately contained a mistake

Prevalence, associated factors and outcomes of pressure injuries in adult intensive care unit patients: the DecubICUs study

Funder: European Society of Intensive Care Medicine; doi: http://dx.doi.org/10.13039/501100013347Funder: Flemish Society for Critical Care NursesAbstract: Purpose: Intensive care unit (ICU) patients are particularly susceptible to developing pressure injuries. Epidemiologic data is however unavailable. We aimed to provide an international picture of the extent of pressure injuries and factors associated with ICU-acquired pressure injuries in adult ICU patients. Methods: International 1-day point-prevalence study; follow-up for outcome assessment until hospital discharge (maximum 12 weeks). Factors associated with ICU-acquired pressure injury and hospital mortality were assessed by generalised linear mixed-effects regression analysis. Results: Data from 13,254 patients in 1117 ICUs (90 countries) revealed 6747 pressure injuries; 3997 (59.2%) were ICU-acquired. Overall prevalence was 26.6% (95% confidence interval [CI] 25.9–27.3). ICU-acquired prevalence was 16.2% (95% CI 15.6–16.8). Sacrum (37%) and heels (19.5%) were most affected. Factors independently associated with ICU-acquired pressure injuries were older age, male sex, being underweight, emergency surgery, higher Simplified Acute Physiology Score II, Braden score 3 days, comorbidities (chronic obstructive pulmonary disease, immunodeficiency), organ support (renal replacement, mechanical ventilation on ICU admission), and being in a low or lower-middle income-economy. Gradually increasing associations with mortality were identified for increasing severity of pressure injury: stage I (odds ratio [OR] 1.5; 95% CI 1.2–1.8), stage II (OR 1.6; 95% CI 1.4–1.9), and stage III or worse (OR 2.8; 95% CI 2.3–3.3). Conclusion: Pressure injuries are common in adult ICU patients. ICU-acquired pressure injuries are associated with mainly intrinsic factors and mortality. Optimal care standards, increased awareness, appropriate resource allocation, and further research into optimal prevention are pivotal to tackle this important patient safety threat

Yoğun Bakımda Deliryum Tedavisinde Dexmedetomidin Kullanımı: Olgu Sunumu

Yoğun bakımda postoperatif kognitif disfonsiyon ve deliryumun görülme sıklığı %30-80’dir ve deliryumun mortalite ve morbiditeyi belirgin olarak arttırdığı bilinmektedir. Tedavisinde non-farmakolojik yöntemlerin yanı sıra farmakolojik tedavilerde kullanılmaktadır. Son dönem yayınlarda deliryum tedavisinde deksmedetomidin kullanımı önerilmektedir. Bu yazıda yoğun bakımda hipoaktif deliryum tablosu olan hastada deksmedetomidin tedavisinin etkisini sunmayı amaçladık