Methodical Bases of an Estimation of the Current Collection of Customs Duties

In the article the methodical bases of the current assessment process of collection of customs payments. The assessment is based on indicators of volume, completeness and relative cost of their collection. Baseline information for assessment are data on the results of the functioning of customs risk management for a specified period of time

Stochastic Model for Assessment of Effective Management of Customs Risks

In article the mathematical model for a quantitative assessment of effective management of customs risks is offered. Feature of model consists in the complex accounting of direct and latent effects of functioning of a control system of customs risks (RMS). The model relies on probability-theoretic representation of process of possible violation of the customs legislation by participants of foreign economic activity

Design and baseline characteristics of the finerenone in reducing cardiovascular mortality and morbidity in diabetic kidney disease trial

Background: Among people with diabetes, those with kidney disease have exceptionally high rates of cardiovascular (CV) morbidity and mortality and progression of their underlying kidney disease. Finerenone is a novel, nonsteroidal, selective mineralocorticoid receptor antagonist that has shown to reduce albuminuria in type 2 diabetes (T2D) patients with chronic kidney disease (CKD) while revealing only a low risk of hyperkalemia. However, the effect of finerenone on CV and renal outcomes has not yet been investigated in long-term trials. Patients and Methods: The Finerenone in Reducing CV Mortality and Morbidity in Diabetic Kidney Disease (FIGARO-DKD) trial aims to assess the efficacy and safety of finerenone compared to placebo at reducing clinically important CV and renal outcomes in T2D patients with CKD. FIGARO-DKD is a randomized, double-blind, placebo-controlled, parallel-group, event-driven trial running in 47 countries with an expected duration of approximately 6 years. FIGARO-DKD randomized 7,437 patients with an estimated glomerular filtration rate >= 25 mL/min/1.73 m(2) and albuminuria (urinary albumin-to-creatinine ratio >= 30 to <= 5,000 mg/g). The study has at least 90% power to detect a 20% reduction in the risk of the primary outcome (overall two-sided significance level alpha = 0.05), the composite of time to first occurrence of CV death, nonfatal myocardial infarction, nonfatal stroke, or hospitalization for heart failure. Conclusions: FIGARO-DKD will determine whether an optimally treated cohort of T2D patients with CKD at high risk of CV and renal events will experience cardiorenal benefits with the addition of finerenone to their treatment regimen. Trial Registration: EudraCT number: 2015-000950-39; ClinicalTrials.gov identifier: NCT02545049

Numerical study of magnetic nanofluids flow in the round channel located in the constant magnetic field

In this paper, the study of ferromagnetic nanoparticles behaviour in the constant magnetic field is carried out. For numerical simulation we have used Euler-Lagrange two-component approach. Using numerical simulation we have studied the growth of deposition of nanoparticles on the channel walls depending on the Reynolds number and the position of the magnet. The flow pattern, the concentration field and the trajectory of nanoparticles as a function of the Reynolds number were obtained. The good qualitative and quantitative agreement between numerical simulation and experiments was shown

Numerical study of magnetic nanofluids flow in the round channel located in the constant magnetic field

In this paper, the study of ferromagnetic nanoparticles behaviour in the constant magnetic field is carried out. For numerical simulation we have used Euler-Lagrange two-component approach. Using numerical simulation we have studied the growth of deposition of nanoparticles on the channel walls depending on the Reynolds number and the position of the magnet. The flow pattern, the concentration field and the trajectory of nanoparticles as a function of the Reynolds number were obtained. The good qualitative and quantitative agreement between numerical simulation and experiments was shown

Numerical study of magnetic nanofluids flow in the round channel located in the constant magnetic field

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Assessment of the marketing and innovative potential of synbiotic products with herbal biocorrector

The article presents the results of studies of the relationship of potential consumers to new synbiotic products with predictably formed functional, prebiotic properties and biological activity. The assessment of the prospects of including the developed bioactive synbiotic products in the recipes of dishes of public catering enterprises and giving them functional properties is given. The main socio-demographic characteristics and preferences of consumers in relation to synbiotic products with compositions of bioactive plant components have been identified. The trends of needs change, their duality, dilemmas, reality and problems of the main drivers relevant to the modern consumer, price expectations, preferred options for introducing bioactive synbiotic products into the diet are revealed. The study allows us to draw a conclusion about the need to take into account when developing new technologies and reflect in the information and advertising materials the identified consumer expectations regarding the taste, usefulness, safety, convenience and authenticity of new products, including synbiotic with plant-based biological active components, and their Introduction into food recipes is a promising direction for the development of enterprises of the HoReCa segment. The results of the study, carried out with a focus on enterprises in the public catering sector, seem relevant, since the use of synbiotic products with herbal biological components is an expansion of opportunities for food and bio-technologies, public catering organizations with justified socio-economic effect

The Open Corpus of the Veps and Karelian Languages: Overview and Applications

Abstract. A growing priority in the study of Baltic-Finnic languages of the Republic of Karelia has been the methods and tools of corpus linguistics. Since 2016, linguists, mathematicians, and programmers at the Karelian Research Centre have been working with the Open Corpus of the Veps and Karelian Languages (VepKar), which is an extension of the Veps Corpus created in 2009. The VepKar corpus comprises texts in Karelian and Veps, multifunctional dictionaries linked to them, and software with an advanced system of search using various criteria of the texts (language, genre, etc.) and numerous linguistic categories (lexical and grammatical search in texts was implemented thanks to the generator of word forms that we created earlier). A corpus of 3000 texts was compiled, texts were uploaded and marked up, the system for classifying texts into languages, dialects, types and genres was introduced, and the word-form generator was created. Future plans include developing a speech module for working with audio recordings and a syntactic tagging module using morphological analysis outputs. Owing to continuous functional advancements in the corpus manager and ongoing VepKar enrichment with new material and text markup, users can handle a wide range of scientific and applied tasks. In creating the universal national VepKar corpus, its developers and managers strive to preserve and exhibit as fully as possible the state of the Veps and Karelian languages in the 1