Verificación documental para la elaboración de Contratos de Compra Venta de bienes inmuebles de personas naturales en Instancia Notarial en el Distrito de Chilca - 2017

Dentro de la legislación Peruana nos encontramos en el sistema notarial latino, donde el notario es un profesional del derecho encargado de dar fé y garantizar la legitimidad de los documentos. Sin embargo, la sociedad al no tener seguridad en la elaboración de actos jurídicos sobre bienes inmuebles se genera el siguiente problema “¿Existe verificación documental para la elaboración de contratos de compra venta de bienes inmuebles de personas naturales en instancia notarial en el distrito de Chilca - 2017?”. La investigación es básica – pura, utilizando los métodos: general: análisis – síntesis, inductivo – deductivo; específico: descriptivo; particulares: literal, sociológico, sistemático; nivel descriptivo, con muestra de 60 expedientes, utilizándose como técnica la ficha de observación concluyéndose que la hipótesis es verdadera, al determinarse que la verificación documental se realiza de forma superficial, para la elaboración de contratos de compra venta de bienes inmuebles entre personas naturales en instancia notarial en el distrito de Chilca – 2017. Sugiriéndose la modificación del art. 16 del DL 1049.Tesi

Mortality from gastrointestinal congenital anomalies at 264 hospitals in 74 low-income, middle-income, and high-income countries: a multicentre, international, prospective cohort study

Summary Background Congenital anomalies are the fifth leading cause of mortality in children younger than 5 years globally. Many gastrointestinal congenital anomalies are fatal without timely access to neonatal surgical care, but few studies have been done on these conditions in low-income and middle-income countries (LMICs). We compared outcomes of the seven most common gastrointestinal congenital anomalies in low-income, middle-income, and high-income countries globally, and identified factors associated with mortality. Methods We did a multicentre, international prospective cohort study of patients younger than 16 years, presenting to hospital for the first time with oesophageal atresia, congenital diaphragmatic hernia, intestinal atresia, gastroschisis, exomphalos, anorectal malformation, and Hirschsprung’s disease. Recruitment was of consecutive patients for a minimum of 1 month between October, 2018, and April, 2019. We collected data on patient demographics, clinical status, interventions, and outcomes using the REDCap platform. Patients were followed up for 30 days after primary intervention, or 30 days after admission if they did not receive an intervention. The primary outcome was all-cause, in-hospital mortality for all conditions combined and each condition individually, stratified by country income status. We did a complete case analysis. Findings We included 3849 patients with 3975 study conditions (560 with oesophageal atresia, 448 with congenital diaphragmatic hernia, 681 with intestinal atresia, 453 with gastroschisis, 325 with exomphalos, 991 with anorectal malformation, and 517 with Hirschsprung’s disease) from 264 hospitals (89 in high-income countries, 166 in middleincome countries, and nine in low-income countries) in 74 countries. Of the 3849 patients, 2231 (58·0%) were male. Median gestational age at birth was 38 weeks (IQR 36–39) and median bodyweight at presentation was 2·8 kg (2·3–3·3). Mortality among all patients was 37 (39·8%) of 93 in low-income countries, 583 (20·4%) of 2860 in middle-income countries, and 50 (5·6%) of 896 in high-income countries (p<0·0001 between all country income groups). Gastroschisis had the greatest difference in mortality between country income strata (nine [90·0%] of ten in lowincome countries, 97 [31·9%] of 304 in middle-income countries, and two [1·4%] of 139 in high-income countries; p≤0·0001 between all country income groups). Factors significantly associated with higher mortality for all patients combined included country income status (low-income vs high-income countries, risk ratio 2·78 [95% CI 1·88–4·11], p<0·0001; middle-income vs high-income countries, 2·11 [1·59–2·79], p<0·0001), sepsis at presentation (1·20 [1·04–1·40], p=0·016), higher American Society of Anesthesiologists (ASA) score at primary intervention (ASA 4–5 vs ASA 1–2, 1·82 [1·40–2·35], p<0·0001; ASA 3 vs ASA 1–2, 1·58, [1·30–1·92], p<0·0001]), surgical safety checklist not used (1·39 [1·02–1·90], p=0·035), and ventilation or parenteral nutrition unavailable when needed (ventilation 1·96, [1·41–2·71], p=0·0001; parenteral nutrition 1·35, [1·05–1·74], p=0·018). Administration of parenteral nutrition (0·61, [0·47–0·79], p=0·0002) and use of a peripherally inserted central catheter (0·65 [0·50–0·86], p=0·0024) or percutaneous central line (0·69 [0·48–1·00], p=0·049) were associated with lower mortality. Interpretation Unacceptable differences in mortality exist for gastrointestinal congenital anomalies between lowincome, middle-income, and high-income countries. Improving access to quality neonatal surgical care in LMICs will be vital to achieve Sustainable Development Goal 3.2 of ending preventable deaths in neonates and children younger than 5 years by 2030

Verificación documental para la elaboración de Contratos de Compra Venta de bienes inmuebles de personas naturales en Instancia Notarial en el Distrito de Chilca - 2017

TesisDentro de la legislación Peruana nos encontramos en el sistema notarial latino, donde el notario es un profesional del derecho encargado de dar fé y garantizar la legitimidad de los documentos. Sin embargo, la sociedad al no tener seguridad en la elaboración de actos jurídicos sobre bienes inmuebles se genera el siguiente problema “¿Existe verificación documental para la elaboración de contratos de compra venta de bienes inmuebles de personas naturales en instancia notarial en el distrito de Chilca - 2017?”. La investigación es básica – pura, utilizando los métodos: general: análisis – síntesis, inductivo – deductivo; específico: descriptivo; particulares: literal, sociológico, sistemático; nivel descriptivo, con muestra de 60 expedientes, utilizándose como técnica la ficha de observación concluyéndose que la hipótesis es verdadera, al determinarse que la verificación documental se realiza de forma superficial, para la elaboración de contratos de compra venta de bienes inmuebles entre personas naturales en instancia notarial en el distrito de Chilca – 2017. Sugiriéndose la modificación del art. 16 del DL 1049

Nivel de conocimiento sobre buena postura en escolares de 5to y 6to de la Institución Educativa “Túpac Amaru II” de Florencia de Mora – Trujillo, 2017

El presente trabajo tiene como objetivo determinar el nivel de conocimiento sobre buena postura en escolares de 5to y 6to de educación primaria de la Institución Educativa “Tupac Amaru II” de Florencia de Mora –Trujillo 2017. Siendo un estudio de tipo descriptivo, retrospectivo, observacional, de corte transversal, de diseño no experimental. La población estuvo conformada por 218 alumnos. El instrumento utilizado fue un formato de recolección de datos. Los resultados obtenidos muestran que un 12.84% presentan buen nivel de conocimiento sobre buena postura, 11.01% sobre buena postura en sedente y 38.99% sobre buena postura respeto al transporte de mochila. Se constata que hay un mal nivel sobre buena postura con un 57.34%, en sedente con un 50.46% y en el transporte de mochila con un 44.04%

A global metagenomic map of urban microbiomes and antimicrobial resistance

We present a global atlas of 4,728 metagenomic samples from mass-transit systems in 60 cities over 3 years, representing the first systematic, worldwide catalog of the urban microbial ecosystem. This atlas provides an annotated, geospatial profile of microbial strains, functional characteristics, antimicrobial resistance (AMR) markers, and genetic elements, including 10,928 viruses, 1,302 bacteria, 2 archaea, and 838,532 CRISPR arrays not found in reference databases. We identified 4,246 known species of urban microorganisms and a consistent set of 31 species found in 97% of samples that were distinct from human commensal organisms. Profiles of AMR genes varied widely in type and density across cities. Cities showed distinct microbial taxonomic signatures that were driven by climate and geographic differences. These results constitute a high-resolution global metagenomic atlas that enables discovery of organisms and genes, highlights potential public health and forensic applications, and provides a culture-independent view of AMR burden in cities.Funding: the Tri-I Program in Computational Biology and Medicine (CBM) funded by NIH grant 1T32GM083937; GitHub; Philip Blood and the Extreme Science and Engineering Discovery Environment (XSEDE), supported by NSF grant number ACI-1548562 and NSF award number ACI-1445606; NASA (NNX14AH50G, NNX17AB26G), the NIH (R01AI151059, R25EB020393, R21AI129851, R35GM138152, U01DA053941); STARR Foundation (I13- 0052); LLS (MCL7001-18, LLS 9238-16, LLS-MCL7001-18); the NSF (1840275); the Bill and Melinda Gates Foundation (OPP1151054); the Alfred P. Sloan Foundation (G-2015-13964); Swiss National Science Foundation grant number 407540_167331; NIH award number UL1TR000457; the US Department of Energy Joint Genome Institute under contract number DE-AC02-05CH11231; the National Energy Research Scientific Computing Center, supported by the Office of Science of the US Department of Energy; Stockholm Health Authority grant SLL 20160933; the Institut Pasteur Korea; an NRF Korea grant (NRF-2014K1A4A7A01074645, 2017M3A9G6068246); the CONICYT Fondecyt Iniciación grants 11140666 and 11160905; Keio University Funds for Individual Research; funds from the Yamagata prefectural government and the city of Tsuruoka; JSPS KAKENHI grant number 20K10436; the bilateral AT-UA collaboration fund (WTZ:UA 02/2019; Ministry of Education and Science of Ukraine, UA:M/84-2019, M/126-2020); Kyiv Academic Univeristy; Ministry of Education and Science of Ukraine project numbers 0118U100290 and 0120U101734; Centro de Excelencia Severo Ochoa 2013–2017; the CERCA Programme / Generalitat de Catalunya; the CRG-Novartis-Africa mobility program 2016; research funds from National Cheng Kung University and the Ministry of Science and Technology; Taiwan (MOST grant number 106-2321-B-006-016); we thank all the volunteers who made sampling NYC possible, Minciencias (project no. 639677758300), CNPq (EDN - 309973/2015-5), the Open Research Fund of Key Laboratory of Advanced Theory and Application in Statistics and Data Science – MOE, ECNU, the Research Grants Council of Hong Kong through project 11215017, National Key RD Project of China (2018YFE0201603), and Shanghai Municipal Science and Technology Major Project (2017SHZDZX01) (L.S.