The temporal changes of the pulsational periods of the pre-white dwarf PG 1159-035

PG 1159-035, a pre-white dwarf with T=140000 K, is the prototype of the PG1159 spectroscopic class and the DOV pulsating class. Changes in the star cause variations in its oscillation periods. The measurement of temporal change in the oscillation periods, dP/dt, allows us to estimate directly rates of stellar evolutionary changes, such as the cooling rate and the envelope contraction rate, providing a way to test and refine evolutionary models for pre-white dwarf pulsating stars. We measured 27 pulsation modes period changes. The periods varied at rates of between 1 and 100 ms/yr, and several can be directly measured with a relative standard uncertainty below 10%. For the 516.0 s mode (the highest in amplitude) in particular, not only the value of dP/dt can be measured directly with a relative standard uncertainty of 2%, but the second order period change, d(dP/dt)/dt, can also be calculated reliably. By using the (O-C) method we refined the dP/dt and estimated the d(dP/dt)/dt for six other pulsation periods. As a first application, we calculated the change in the PG 1559-035 rotation period, dP_rot/dt = -2.13*10^{-6} s/s, the envelope contraction rate dR/dt = -2.2*10^{-13} solar radius/s, and the cooling rante dT/dt = -1.42*10^{-3} K/s.Comment: 8 pages; 2 figures; 2 tables; appendix with 2 table

Incremental Distance Transforms (IDT)

A new generic scheme for incremental implementations of distance transforms (DT) is presented: Incremental Distance Transforms (IDT). This scheme is applied on the cityblock, Chamfer, and three recent exact Euclidean DT (E2DT). A benchmark shows that for all five DT, the incremental implementation results in a significant speedup: 3.4×−10×. However, significant differences (i.e., up to 12.5×) among the DT remain present. The FEED transform, one of the recent E2DT, even showed to be faster than both city-block and Chamfer DT. So, through a very efficient incremental processing scheme for DT, a relief is found for E2DT’s computational burden

Real-time power system dynamic security assessment based on advanced feature selection for decision tree classifiers

This paper proposed a novel algorithm based on advanced feature selection technique for decision tree (DT) classifier to assess the dynamic security in power system. The proposed methodology utilized symmetrical uncertainty (SU) to reduce the data redundancy in a dataset for DT classifier based dynamic security assessment (DSA) tools. The results show that SU reduces the dimension of the dataset used for DSA significantly. Subsequently, the approach improves the performance of DT classifier. The effectiveness of the proposed technique is demonstrated on modified IEEE 30-bus test system model. The results show that the DT classifier with SU outperform the DT classifier without SU. The performance of the proposed algorithm indicates that the DT classifier with SU is able to assess the dynamic security of the system in near real-time. Therefore, it is able to provide vital information for protection and control application in power system operation

Nonlinear Seebeck Effect in a Model Granular Superconductor

The change of the Josephson supercurrent density of a weakly-connected granular superconductor in response to externally applied arbitrary thermal gradient dT/dx (nonlinear Seebeck effect) is considered within a model of 3D Josephson junction arrays. For dT/dx>(dT/dx)_c, where (dT/dx)_c is estimated to be of the order of 10^4 K/m for YBCO ceramics with an average grain's size of 10 microns, the weak-links-dominated thermopower S (Seebeck coefficient) is predicted to become strongly dT/dx-dependent.Comment: REVTEX, no figure

Immunogenicity and protective efficacy of an anti-Streptococcus pyogenes vaccine candidate in multiple animal species

Streptococcus pyogenes, also known as Group A Streptococcus (GAS) has been associated with a range of diseases from the mild pharyngitis and pyoderma to more severe invasive infections such as streptococcal toxic shock. GAS also causes a number of non-suppurative post-infectious diseases such as rheumatic fever, rheumatic heart disease and glomerulonephritis. The large extent of GAS disease burden necessitates the need for a prophylactic vaccine that could target the diverse GAS emm types circulating globally. Anti-GAS vaccine strategies have focused primarily on the GAS M-protein, an extracellular virulence factor anchored to GAS cell wall. As opposed to the hypervariable N-terminal region, the C-terminal portion of the protein is highly conserved among different GAS emm types and is the focus of a leading GAS vaccine candidate, J8-DT/alum. The vaccine candidate J8-DT/alum was shown to be immunogenic in mice, rabbits and the non-human primates, hamadryas baboons. Similar responses to J8-DT/alum were observed after subcutaneous and intramuscular immunization with J8-DT/alum, in mice and in rabbits. Further assessment of parameters that may influence the immunogenicity of J8-DT demonstrated that the immune responses were identical in male and female mice and the use of alum as an adjuvant in the vaccine formulation significantly increased its immunogenicity, resulting in a long-lived serum IgG response. Contrary to the previous findings, the data in this thesis indicates that a primary immunization with J8-DT/alum (50ƒÊg) followed by a single boost is sufficient to generate a robust immune response in mice. As expected, the IgG response to J8- DT/alum was a Th2 type response consisting predominantly of the isotype IgG1 accompanied by lower levels of IgG2a. Intramuscular vaccination of rabbits with J8-DT/alum demonstrated that an increase in the dose of J8-DT/alum up to 500ƒÊg does not have an impact on the serum IgG titers achieved. Similar to the immune response in mice, immunization with J8-DT/alum in baboons also established that a 60ƒÊg dose compared to either 30ƒÊg or 120ƒÊg was sufficient to generate a robust immune response. Interestingly, mucosal infection of naive baboons with a M1 GAS strain did not induce a J8-specific serum IgG response. As J8-DT/alum mediated protection has been previously reported to be due to the J8- specific antibody formed, the efficacy of J8-DT antibodies was determined in vitro and in vivo. In vitro opsonization and in vivo passive transfer confirmed the protective potential of J8-DT antibodies. A reduction in the bacterial burden after challenge with a bioluminescent M49 GAS strain in mice that were passively administered J8-DT IgG established that protection due to J8-DT was mediated by antibodies. The GAS burden in infected mice was monitored using bioluminescent imaging in addition to traditional CFU assays. Bioluminescent GAS strains including the ‘rheumatogenic’ M1 GAS could not be generated due to limitations with transformation of GAS, however, a M49 GAS strain was utilized during BLI. The M49 serotype is traditionally a ‘nephritogenic’ serotype associated with post-streptococcal glomerulonephritis. Anti- J8-DT antibodies now have been shown to be protective against multiple GAS strains such as M49 and M1. This study evaluated the immunogenicity of J8-DT/alum in different species of experimental animals in preparation for phase I human clinical trials and provided the ground work for the development of a rapid non-invasive assay for evaluation of vaccine candidates

The non-microstates free entropy dimension of DT-operators

Dykema and Haagerup introduced the class of DT-operators and also showed that every DT-operator generate the von Neumann algebra generated by the free group on two generators. In this paper we prove that Voiculescu's non-microstates free entropy dimension is 2 for all DT-operators.Comment: 30 page