“A Supernova that Sparks in Every Direction”: A Long-Term Assessment of the Research Sprints Faculty Engagement Program

Article will be published in College & Research Libraries in March 2024. This is the accepted version of the manuscript prior to copyediting.PREPRINT: Article to be published in College & Research Libraries in March 2024. This is the accepted version of the manuscript prior to copyediting. The Research Sprints program offers faculty partners the opportunity to collaborate intensively and exclusively for one week with a team of librarians to achieve significant progress on research or teaching projects. This longitudinal study extends previous immediate and short-term assessments by interviewing Research Sprints participants at two research-intensive institutions 2-4 years after their concentrated week. The authors evaluate the enduring impact of the program on the participants’ projects, research/teaching practices, and relationships with the library. Participants report achieving project goals, improved skills and student success, and greater awareness and appreciation of librarians’ work

The Public Digital Humanities Institute - A National Endowment for the Humanities Institute to Support Academic & Community Collaborations in the Digital Humanities

The Public Digital Humanities Institute (PDHI) brought together teams of academics and community partners from 12 community-based digital humanities projects for an intensive week of digital humanities training and discussion at the University of Kansas (KU) in Lawrence, Kansas. The PDHI was funded by the National Endowment for the Humanities through the Institute for Advanced Topics in the Digital Humanities program. It was organized and carried out by KU’s Institute for Digital Research in the Humanities (IDRH), under the direction of co-PI’s digital scholarly initiatives librarian Brian Rosenblum and professor of communication studies Dave Tell. This white paper discusses the PDHI's origins & goals, participating projects, curriculum & activities and outcomes. The PDHI Handbook provides access to slides, handouts and other resources presented at the Institute.National Endowment for the Humanitie

Production of the cylinder head and crankcase of a small internal combustion engine using metal laser powder bed fusion

This effort investigates the use of metal additive manufacturing, specifically laser powder bed fusion (LPBF) for the automotive and defense industries by demonstrating its feasibility to produce working internal combustion (IC) engine components. Through reverse engineering, model modifications, parameter selection, build layout optimization, and support structure design, the production of a titanium crankcase and aluminum cylinder head for a small IC engine was made possible. Computed tomography (CT) scans were subsequently used to quantify whether defects such as cracks, geometric deviations, and porosity were present or critical. Once viability of the parts was established, machining and other post-possessing were completed to create functional parts. Final X-ray CT and micro-CT results showed all critical features fell within ±0.127 mm of the original equipment manufacturer (OEM) parts. This allowed reassembly of the engine without any issues hindering later successful operation. Furthermore, the LPBF parts had significantly reduced porosity percentages, potentially making them more robust than their cast counterparts

A ferritin-based COVID-19 nanoparticle vaccine that elicits robust, durable, broad-spectrum neutralizing antisera in non-human primates

While the rapid development of COVID-19 vaccines has been a scientific triumph, the need remains for a globally available vaccine that provides longer-lasting immunity against present and future SARS-CoV-2 variants of concern (VOCs). Here, we describe DCFHP, a ferritin-based, protein-nanoparticle vaccine candidate that, when formulated with aluminum hydroxide as the sole adjuvant (DCFHP-alum), elicits potent and durable neutralizing antisera in non-human primates against known VOCs, including Omicron BQ.1, as well as against SARS-CoV-1. Following a booster ~one year after the initial immunization, DCFHP-alum elicits a robust anamnestic response. To enable global accessibility, we generated a cell line that can enable production of thousands of vaccine doses per liter of cell culture and show that DCFHP-alum maintains potency for at least 14 days at temperatures exceeding standard room temperature. DCFHP-alum has potential as a once-yearly (or less frequent) booster vaccine, and as a primary vaccine for pediatric use including in infants

Preliminary Evidence That Fiji Water Has Protective Effects against Aluminum Toxicity in Honey Bees (Apis mellifera)

Researchers have determined that bioavailable aluminum chloride (AlCl3) may affect honey bee behavior (e.g., foraging patterns and locomotion) and physiology (e.g., abdominal spasms). The purpose of these experiments was to determine if Fiji water reduces the impacts of AlCl3 toxicity in bees by measuring circadian rhythmicity (number of times bees crossed the centerline during the day and night), average daily activity (average number of times bees crossed the centerline per day), and mortality rates (average number of days survived) using an automated monitor apparatus. Overall, the AlCl3 before and after Fiji groups had significantly higher average daily activity and rhythmicity rates compared to their respective AlCl3 before and after deionized water (DI) groups. One of the AlCl3 before DI groups exhibited no difference in rhythmicity rates compared to its respective AlCl3 after Fiji group. Overall, these results suggest that Fiji water might exert protective effects against AlCl3. The AlCl3 groups paired with Fiji water had higher activity and rhythmicity levels compared to the AlCl3 groups paired with DI. It is important for researchers to continue to study aluminum and possible preventatives for aluminum uptake

Hyper-palatable foods in elementary school lunches: Availability and contributing factors in a national sample of US public schools

Background School cafeterias are a major point of influence for child nutrition. United States federal legislation requires the presence of important nutrients in school meals. However, legislation overlooks the potential presence of hyper-palatable foods in school lunches, a hypothesized factor that may influence children’s eating behavior and obesity risk. The study sought to 1) quantify the prevalence of hyper-palatable foods (HPF) served in US elementary school lunches; and 2) determine whether food hyper-palatability varied based on school geographic region (East/Central/West), urbanicity (urban/micropolitan/rural), or meal item (entrée/side/fruit or vegetable). Methods Lunch menu data (N = 18 menus; N = 1160 total foods) were collected from a sample of six states that represented geographic regions of the United States (Eastern/Central/Western; Northern/Southern) and that had variability in urbanicity (urban, micropolitan, and rural) within each state. A standardized definition from Fazzino et al (2019) was used to identify HPF in lunch menus. Results HPF comprised almost half of foods in school lunches (M = 47%; SD = 5%). Compared to fruit/vegetable items, entrées were >23 times more likely to be hyper-palatable and side dishes were >13 times more likely to be hyper-palatable (p values .05). The majority of entrée and side items contained meat/meat alternatives and/or grains and likely aligned with the US federal reimbursable meal components of meat/meat alternatives and/or grains. Conclusions and implications HPF comprised almost half of foods offered in elementary school lunches. Entrées and side items were most likely to be hyper-palatable. US school lunches may be a key point of regular exposure to HPF among young children, a risk factor that may elevate child obesity risk. Public policy regulating HPF in school meals may be needed to protect children’s health

Mapping the global distribution of invasive pest Drosophila suzukii and parasitoid Leptopilina japonica: Implications for biological control

Insect pest invasions cause significant damage to crop yields, and the resultant economic losses are truly alarming. Climate change and trade liberalization have opened new ways of pest invasions. Given the consumer preference towards organic agricultural products and environment-friendly nature of natural pest control strategies, biological control is considered to be one of the potential options for managing invasive insect pests. Drosophila suzukii (Drosophilidae) is an extremely damaging fruit pest, demanding development of effective and sustainable biological control strategies. In this study, we assessed the potential of the parasitoid Leptopilina japonica (Figitidae) as a biocontrol agent for D. suzukii using ecological niche modeling approaches. We developed global-scale models for both pest and parasitoid to identify four components necessary to derive a niche based, target oriented prioritization approach to plan biological control programs for D. suzukii: (i) potential distribution of pest D. suzukii, (ii) potential distribution of parasitoid L. japonica, (iii) the degree of overlap in potential distributions of pest and parasitoid, and (iv) biocontrol potential of this system for each country. Overlapping suitable areas of pest and parasitoid were identified at two different thresholds and at the most desirable threshold (E = 5%), potential for L. japonica mediated biocontrol management existed in 125 countries covering 1.87 × 107 km2, and at the maximum permitted threshold (E = 10%), land coverage was reduced to 1.44 × 107 km2 in 121 countries. Fly pest distributional information as a predictor variable was not found to be improving parasitoid model performance, and globally, only in half of the countries, >50% biocontrol coverage was estimated. We therefore suggest that niche specificities of both pest and parasitoid must be included in site-specific release planning of L. japonica for effective biocontrol management aimed at D. suzukii. This study can be extended to design cost-effective pre-assessment strategies for implementing any biological control management program

Linking Community Resilience to Health and Wellness

Community Resilience (CR) is a topic on many people’s minds these days, and represents a community’s and an individual’s ability to weather adversity, as well as to adapt and recover. It also represents a community’s strength and readiness to respond to changes and capitalize on opportunities. Adaptation and recovery are intrinsically linked to the health and wellness of a community or individual, and measuring the link between CR and a community’s health is a point of key importance. Community resilience is complex, so scholars and stakeholders have developed a variety of models and metrics to measure and identify it. Many of these are linked to health and wellness outcomes within the community, providing a foundation for the link between the resilience of a community and the health of the people. Further research is required as the nature of CR is better defined, but current results provide support for using the measurement of CR to identify key points of intervention to improve the health and wellbeing of communities

Genome sequence of Ophryocystis elektroscirrha, an apicomplexan parasite of monarch butterflies: cryptic diversity and response to host-sequestered plant chemicals

Apicomplexa are ancient and diverse organisms which have been poorly characterized by modern genomics. To better understand the evolution and diversity of these single-celled eukaryotes, we sequenced the genome of Ophryocystis elektroscirrha, a parasite of monarch butterflies, Danaus plexippus. We contextualize our newly generated resources within apicomplexan genomics before answering longstanding questions specific to this host-parasite system. To start, the genome is miniscule, totaling only 9 million bases and containing fewer than 3,000 genes, half the gene content of two other sequenced invertebrate-infecting apicomplexans, Porospora gigantea and Gregarina niphandrodes. We found that O. elektroscirrha shares different orthologs with each sequenced relative, suggesting the true set of universally conserved apicomplexan genes is very small indeed. Next, we show that sequencing data from other potential host butterflies can be used to diagnose infection status as well as to study diversity of parasite sequences. We recovered a similarly sized parasite genome from another butterfly, Danaus chrysippus, that was highly diverged from the O. elektroscirrha reference, possibly representing a distinct species. Using these two new genomes, we investigated potential evolutionary response by parasites to toxic phytochemicals their hosts ingest and sequester. Monarch butterflies are well-known to tolerate toxic cardenolides thanks to changes in the sequence of their Type II ATPase sodium pumps. We show that Ophryocystis completely lacks Type II or Type 4 sodium pumps, and related proteins PMCA calcium pumps show extreme sequence divergence compared to other Apicomplexa, demonstrating new avenues of research opened by genome sequencing of non-model Apicomplexa

From single attitudes to belief systems: Examining the centrality of STEM attitudes using belief network analysis

Many achievement and motivation theories claim that a specific set of beliefs, interests or values plays a central role in determining career choice and behavior. In order to investigate how attitudes determine behaviors, researchers generally investigate each attitude in isolation. This article argues that studying belief systems rather than single attitudes has several explanatory advantages. In particular, a system-level approach can provide clear definitions and measures of attitude importance. Using a nationally representative sample of 13,283 9th graders and measures of 136 STEM-related attitudes, I implement a belief network analysis to investigate which attitudes are most influential in determining STEM career choice. The results suggest that identity beliefs, educational expectations and ability-related beliefs play central roles in individuals’ belief systems