5,777 research outputs found

    Jet Grouting to Reduce Liquefaction Potential

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    A compaction sand piling technique was abandoned after it caused excessive vibrations in buildings adjacent to the construction site. Various alternatives were evaluated, but none could provide certainty of acceptance by the residential community without causing schedule delay and other construction complications. A vibration-free jet grouting method was, therefore adopted for ground improvement to reduce liquefaction potential at the site. Modifications in grouting procedure details were implemented to overcome problems caused by the site conditions

    Astragaloside II promotes intestinal epithelial repair by enhancing L-arginine uptake and activating the mTOR pathway

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    Astragaloside II (AS II) extracted from Astragalus membranaceus has been reported to promote tissue wound repair. However, the effect of AS II on inflammatory bowel disease is unknown. We investigated the effects and mechanism of AS II on intestinal wound healing in both in vitro and in vivo models. Human intestinal Caco-2 cells were treated with multiple concentrations of AS II to assess cell proliferation, scratch wound closure, L-arginine uptake, cationic amino acid transporter activity, and activation of the mTOR signaling pathway. These effects were also measured in a mouse model of colitis. AS II promoted wound closure and increased cell proliferation, L-arginine uptake, CAT1 and CAT2 protein levels, total protein synthesis, and phosphorylation of mTOR, S6K, and 4E-BP1 in Caco-2 cells. These effects were suppressed by lysine or rapamycin treatment, suggesting that the enhanced arginine uptake mediates AS II-induced wound healing. Similar results were also observed in vivo. Our findings indicate that AS II can contribute to epithelial barrier repair following intestinal injury, and may offer a therapeutic avenue in treating irritable bowel disease

    The flow and turbulence structure at a rectangular bridge pier with a low angle of attack

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    River hydrodynamicsInteraction with structure

    Probing Top-Quark Couplings at Polarized NLC

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    The energy spectrum of the lepton(s) in e^+e^- --> tt-bar --> l^{+-} ...../l^+l^-..... at next linear colliders (NLC) is studied for arbitrary longitudinal beam polarizations as a possible test of new physics in top-quark couplings. The most general non-standard couplings for gamma-tt-bar, Ztt-bar and Wtb vertices are considered. Expected precision of the non-standard-parameter determination is estimated applying the optimal-observable procedure.Comment: Final version, To appear in Phys. Rev.

    Water Requirements For Waterfowl Areas Near the Great Salt Lake Parts V-VI

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    This report reviews activities on this project since the Progress Report, Part IV, June 1961. The summer of 1961 has been one of the driest on record for Ogden Bay and Howard Slough Refuge. The extreme shortage of irrigation water has resulted in very little flow in the Howard Slough which originates from return flow. The available water from the Weber River for the Ogden Bay Refuge was also the lowest on record. The scarcity of water at these two refuges has resulted in increased salinity. Most of the routine work on the project during the summer was done by Ming Change Tsai, graduate assistant in civil engineering who resided at the Ogden Bay Refuge. Mr. Tsai has been assisted in the care of the salinity lysimiters at Ogden Bay Refuge, and in the salinity surveys at the other refuges by Daya Kaushik, graduate assistant in wildlife resources
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