Hugh Miller: stonemason, geologist, writer

Hugh Miller was born in 1802 in Cromarty, Ross-shire. He started his working life as a stonemason’s apprentice; he later became a social commentator and crusader. His was a household name in his lifetime, not only in Scotland but across the English-speaking world. A recent revival in Scottish history and culture, and a reassessment of the 19th century debates in science, geology and religion, have all led to a fuller appreciation of the rich and complex stories in which Hugh Miller played a part, and of the man himself. With the benefit of recent research for the 2002 conferences, this biography does full justice to the self-educated man, a figure of renown in the 19th century whose literary genius and scientific acumen still resonate in the 21s

Quantum metrology and its application in biology

Quantum metrology provides a route to overcome practical limits in sensing devices. It holds particular relevance to biology, where sensitivity and resolution constraints restrict applications both in fundamental biophysics and in medicine. Here, we review quantum metrology from this biological context, focusing on optical techniques due to their particular relevance for biological imaging, sensing, and stimulation. Our understanding of quantum mechanics has already enabled important applications in biology, including positron emission tomography (PET) with entangled photons, magnetic resonance imaging (MRI) using nuclear magnetic resonance, and bio-magnetic imaging with superconducting quantum interference devices (SQUIDs). In quantum metrology an even greater range of applications arise from the ability to not just understand, but to engineer, coherence and correlations at the quantum level. In the past few years, quite dramatic progress has been seen in applying these ideas into biological systems. Capabilities that have been demonstrated include enhanced sensitivity and resolution, immunity to imaging artifacts and technical noise, and characterization of the biological response to light at the single-photon level. New quantum measurement techniques offer even greater promise, raising the prospect for improved multi-photon microscopy and magnetic imaging, among many other possible applications. Realization of this potential will require cross-disciplinary input from researchers in both biology and quantum physics. In this review we seek to communicate the developments of quantum metrology in a way that is accessible to biologists and biophysicists, while providing sufficient detail to allow the interested reader to obtain a solid understanding of the field. We further seek to introduce quantum physicists to some of the central challenges of optical measurements in biological science.Comment: Submitted review article, comments and suggestions welcom

Charles W. Peach, palaeobotany and Scotland

The move south from Wick to the city of Edinburgh in 1865, some four years after retirement from the Customs service, provided Charles W. Peach with new opportunities for fossil-collecting and scientific networking. Here he renewed and maintained his interest in natural history and made significant palaeobotanical collections from the Carboniferous of the Midland Valley of Scotland. These are distinguished by some interesting characteristics of their documentation which the following generations of fossil collectors and researchers would have done well to emulate. Many of his fossil plant specimens have not only the locality detail,but also the date, month and year of collection neatly handwritten on attached paper labels; as a result, we can follow Peach's collecting activities over a period of some 18 years or so. Comments and even illustrative sketches on the labels of some fossils give us first-hand insight into Peach's observations. Study of these collections now held in National Museums Scotland reveals a pattern of collecting heavily biased towards those localities readily accessible from the newly expanding railways which provided a relatively inexpensive and convenient means of exploring the geology of the neighbourhood of Edinburgh. Charles W. Peach had a very 'hands-on' practical approach to scientific investigation which led him to construct novel glass plates with mounted Sphenopteris cuticle, removed intact from Lower Carboniferous shales and limestones originating in West Lothian. These resemble the herbarium sheets with which he was familiar from his parallel and highly significant work on extant flora including nearshore marine algae. He also prepared hand ground glass microscope slides,particularly of permineralised plant material from Pettycur in Fife, using whatever materials he had to hand at the time. Peach's collection raises questions about the evolution of accepted standards of documentation in private collections, in parallel with the evolution of collecting practices by the new professionals such as the workers of the Geological Survey. Its relatively rapid deposition in museums,compared to many private collections, may also have contributed to its apparently high rate of usage by contemporary workers

ARE U.S. FARM PROGRAMS GOOD PUBLIC POLICY? TAKING POLICY PERFORMANCE SERIOUSLY

Distributional analysis is employed to assess the ethical acceptability of agricultural policy along plurastic moral criteria. Using 1999 micro-data from USDA ARMS survey and the Federal Reserve's Survey of Consumer Finances, we discuss policy performance (measured as the effect of direct government payments on the distribution of incomes and profits) relative to policy goals. We show that current programs only minimally address the post-?farm problem? objective of providing a safety net, and the goal of providing an abundant supply of agricultural products is potentially well-implemented given institutional constraints.Agricultural and Food Policy,

Mrs Alicia Moore, dedicatee of Henry Rowland Brown’s 1859 guidebook Beauties of Lyme Regis

The 1859 second edition of the guidebook The Beauties of Lyme Regis, by Henry Rowland Brown (1837-1921) of Lyme Regis, was dedicated to ‘Mrs Moore’. She is identified here as Alicia Anne Moore née Radford (bap. 1790-1873), Sheffield-born author and novelist, who was descended from the Lymen (or Leman or Lemman) family of Lyme Regis. She may have been a friend of George Roberts (bap. 1804-60), Lyme historian and mayor. Her peripatetic life with her second husband Robert Moore, spent partly overseas and in the Channel Islands (with good links to Lyme Regis), apparently arose from a disastrous first marriage and a technically bigamous second marriage

Fundamental constraints on particle tracking with optical tweezers

A general quantum limit to the sensitivity of particle position measurements is derived following the simple principle of the Heisenberg microscope. The value of this limit is calculated for particles in the Rayleigh and Mie scattering regimes, and with parameters which are relevant to optical tweezers experiments. The minimum power required to observe the zero-point motion of a levitating bead is also calculated, with the optimal particle diameter always smaller than the wavelength. We show that recent optical tweezers experiments are within two orders of magnitude of quantum limited sensitivity, suggesting that quantum optical resources may soon play an important role in high sensitivity tracking applications