Traditional and Current Food Use of Wild Plants Listed in the Russian Pharmacopoeia

Historically Russia can be regarded as a “herbophilious” society. For centuries the multinational population of Russia has used plants in daily diet and for self-medication. The specificity of dietary uptake of medicinal plants (especially those in the unique and highly developed Russian herbal medical tradition) has remained mostly unknown in other regions. Based on 11th edition of the State Pharmacopoeia of the USSR, we selected 70 wild plant species which have been used in food by local Russian populations. Empirical searches were conducted via the Russian-wide applied online database E-library.ru, library catalogs of public libraries in St-Petersburg, the databases Scopus, Web of Science, PubMed, and search engine Google Scholar. The large majority of species included in Russian Pharmacopoeia are used as food by local population, however, aerial parts are more widely used for food. In this review, we summarize data on medicinal species published in Russia and other countries that are included in the Russian Pharmacopoeia and have being used in food for a long time. Consequently, the Russian Pharmacopoeia is an important source of information on plant species used traditionally at the interface of food and medicine. At the same time, there are the so-called “functional foods”, which denotes foods that not only serves to provide nutrition but also can be a source for prevention and cure of various diseases. This review highlights the potential of wild species of Russia monographed in its pharmacopeia for further developing new functional foods and—through the lens of their incorporation into the pharmacopeia—showcases the species' importance in Russia

Formación del modelo óptimo del cluster industrial de empresas de confección chinas basado en la gestión de la zona económica estratégica

El artículo analiza el mecanismo para desarrollar un modelo óptimo de un clúster industrial asociado con la formación de zonas económicas estratégicas utilizando el ejemplo de las empresas textiles chinas. se está resolviendo el problema de determinar el conjunto óptimo de zonas económicas estratégicas prometedoras para maximizar los ingresos de las ventas de productos de clúster industrial en un conjunto dado de zonas económicas estratégicas. se determina la condición de la empresa, que se corresponde más estrechamente con las necesidades del mercado en cuanto al volumen y la variedad de productos de acuerdo con la composición y capacidad de las áreas estratégicas de negocios. se está buscando una política de inversión e innovación que asegure la transformación evolutiva de la arquitectura empresarial de acuerdo con la visión del estado actual y basada en minimizar las inversiones atraídas. se investigan el enfoque de clúster y la integración vertical, lo que puede proporcionar una ventaja competitiva sostenible para las empresas de la industria ligera durante muchos años. se propone y prueba un modelo original para crear un grupo industrial en el ejemplo de las empresas de costura en china

The Pharmacokinetics of Fucoidan after Topical Application to Rats

Fucoidan, a fucose-rich polysaccharide from brown algae, has been used for transdermal formulations targeting inflammatory skin conditions, for the treatment of thrombosis, vascular permeability diseases, subcutaneous wounds, and burns. However, the pharmacokinetics of fucoidan after topical application has not been described. In this study, an ointment (OF) containing 15% fucoidan was topically applied to rats at the doses of 50–150 mg/g. The anti-Xa activity was selected as the biomarker, and the amidolytic assay method was validated and applied for pharmacokinetic studies of fucoidan. Fucoidan in OF penetrated the skin and distributed into the skin, striated muscle, and plasma with AUC0–48 = 0.94 μg·h/g, 2.22 μg·h/g, and 1.92 µg·h/mL, respectively. The longest half-life for fucoidan was observed in plasma, then in striated muscle and skin. It was found that the pharmacokinetics of fucoidan after topical OF application was linear, in the range of 50–150 mg/kg. No accumulation of fucoidan in plasma was observed after repeated topical applications of 100 mg/kg during five days. Our results support the rationality of topical application of formulations with fucoidan

The Pharmacokinetics of Fucoidan after Topical Application to Rats

Fucoidan, a fucose-rich polysaccharide from brown algae, has been used for transdermal formulations targeting inflammatory skin conditions, for the treatment of thrombosis, vascular permeability diseases, subcutaneous wounds, and burns. However, the pharmacokinetics of fucoidan after topical application has not been described. In this study, an ointment (OF) containing 15% fucoidan was topically applied to rats at the doses of 50–150 mg/g. The anti-Xa activity was selected as the biomarker, and the amidolytic assay method was validated and applied for pharmacokinetic studies of fucoidan. Fucoidan in OF penetrated the skin and distributed into the skin, striated muscle, and plasma with AUC0–48 = 0.94 μg·h/g, 2.22 μg·h/g, and 1.92 µg·h/mL, respectively. The longest half-life for fucoidan was observed in plasma, then in striated muscle and skin. It was found that the pharmacokinetics of fucoidan after topical OF application was linear, in the range of 50–150 mg/kg. No accumulation of fucoidan in plasma was observed after repeated topical applications of 100 mg/kg during five days. Our results support the rationality of topical application of formulations with fucoidan

Variation of arbutin content in Bergenia sp. leaves

The common garden perennial, Bergenia, should be utilized as a special new crop for raw material production in the cosmetic industry, producing arbutin. Under open field and full sun conditions, the arbutin contents of Bergenia leaves have not changed significantly